eF-site ID 3rxb-A PDB Code 3rxb Chain A click to enlarge Title Crystal structure of Trypsin complexed with 4-guanidinobutanoic acid Classification HYDROLASE/HYDROLASE INHIBITOR Compound Cationic trypsin Source ORGANISM_COMMON: bovine; ORGANISM_SCIENTIFIC: Bos taurus; Sequence A:  IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAH CYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNT LNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISG WGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNM FCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQK NKPGVYTKVCNYVSWIKQTIASN Description Functional site 1) chain A residue 70 type sequence E description BINDING SITE FOR RESIDUE CA A 1 source : AC1 2) chain A residue 72 type sequence N description BINDING SITE FOR RESIDUE CA A 1 source : AC1 3) chain A residue 75 type sequence V description BINDING SITE FOR RESIDUE CA A 1 source : AC1 4) chain A residue 80 type sequence E description BINDING SITE FOR RESIDUE CA A 1 source : AC1 5) chain A residue 76 type sequence V description BINDING SITE FOR RESIDUE GOL A 2 source : AC2 6) chain A residue 80 type sequence E description BINDING SITE FOR RESIDUE GOL A 2 source : AC2 7) chain A residue 81 type sequence Q description BINDING SITE FOR RESIDUE GOL A 2 source : AC2 8) chain A residue 82 type sequence F description BINDING SITE FOR RESIDUE GOL A 2 source : AC2 9) chain A residue 133 type sequence Q description BINDING SITE FOR RESIDUE GOL A 3 source : AC3 10) chain A residue 134 type sequence C description BINDING SITE FOR RESIDUE GOL A 3 source : AC3 11) chain A residue 135 type sequence L description BINDING SITE FOR RESIDUE GOL A 3 source : AC3 12) chain A residue 157 type sequence K description BINDING SITE FOR RESIDUE GOL A 3 source : AC3 13) chain A residue 162 type sequence S description BINDING SITE FOR RESIDUE DMS A 4 source : AC4 14) chain A residue 163 type sequence D description BINDING SITE FOR RESIDUE DMS A 4 source : AC4 15) chain A residue 164 type sequence S description BINDING SITE FOR RESIDUE DMS A 4 source : AC4 16) chain A residue 167 type sequence K description BINDING SITE FOR RESIDUE DMS A 5 source : AC5 17) chain A residue 172 type sequence G description BINDING SITE FOR RESIDUE DMS A 5 source : AC5 18) chain A residue 189 type sequence D description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 19) chain A residue 190 type sequence S description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 20) chain A residue 191 type sequence C description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 21) chain A residue 195 type sequence S description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 22) chain A residue 211 type sequence W description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 23) chain A residue 212 type sequence G description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 24) chain A residue 214 type sequence G description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 25) chain A residue 222 type sequence G description BINDING SITE FOR RESIDUE ALG A 6 source : AC6 26) chain A residue 54-59 type prosite sequence VSAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC source prosite : PS00134 27) chain A residue 189-200 type prosite sequence DSCQGDSGGPVV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV source prosite : PS00135 28) chain A residue 58 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 29) chain A residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 30) chain A residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 31) chain A residue 75 type BINDING sequence V description source Swiss-Prot : SWS_FT_FI2 32) chain A residue 80 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 33) chain A residue 189 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI2 34) chain A residue 192 type BINDING sequence Q description source Swiss-Prot : SWS_FT_FI2 35) chain A residue 195 type BINDING sequence S description source Swiss-Prot : SWS_FT_FI2 36) chain A residue 70 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 37) chain A residue 72 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI2

Display surface Download Links