eF-site ID 3rv0-ABCD PDB Code 3rv0 Chain A, B, C, D click to enlarge Title Crystal structure of K. polysporus Dcr1 without the C-terminal dsRBD Classification RNA BINDING PROTEIN Compound K. polysporus Dcr1 Source Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus) (A7TR32_VANPO) Sequence A:  SNELKVREFYRLHNACVKLKESIKLIYENPLVTDQNVLNL GTAENTIDYTILNTPTLNVAKTLLGNRYSLDLIDLFQSHD FKDSNTDVDMFIKYPVVYDENLENLAFMHKSFPAHLNDAQ KTQLSNERLEFLGDSWLGALVSYIVYTRFPSANEGMLSQM KESIVNNNNLFDWSTKLNFTKRLQGNIATPKDKMSKRYAD CVEAYIGALVIDRFGTEFLDIKEWLEELSEKKLAKSSQM B:  SNELKVREFYRLHNACVKLKESIKLIYENPLVTDQNVLNL GTAENTIDYTILNTPTLNVAKTLLGNRYSLDLIDLFQSHD FKDSNTDVDMFIKYPVVYDENLENLAFMHKDAQKTQLSNE RLEFLGDSWLGALVSYIVYTRFPSANEGMLSQMKESIVNN NNLFDWSTKLNFTKRLQGNIADKMSKRYADCVEAYIGALV IDRFGTEFLDIKEWLEELSEKKLAKPLNKNAKNELAELLQ INKLGHKLHYRKLTEMPPFRVEVKIGDILLDEAEGNSIRE AEHRAAMKVLENDELLRKYSVYDL C:  SNELKVREFYRLHNACVKLKESIKLIYENPLVTDQNVLNL GTAENTIDYTILNTPTLNVAKTLLGNRYSLDLIDLFQSHD FKDSNTDVDMFIKYPVVYDENLENLAFMHKTQLSNERLEF LGDSWLGALVSYIVYTRFPSANEGMLSQMKESIVNNNNLF DWSTKLNFTKRLQGNIATPTRVVKDKMSKRYADCVEAYIG ALVIDRFGTEFLDIKEWLEELSEKKLAK D:  SNELKVREFYRLHNACVKLKESIKLIYENPLVTDQNVLNL GTAENTIDYTILNTPTLNVAKTLLGNRYSLDLIDLFQSHD FKDSNTDVDMFIKYPVVYDENLENLAFMHKSFTQLSNERL EFLGDSWLGALVSYIVYTRFPSANEGMLSQMKESIVNNNN LFDWSTKLNFTKRLQGNIATPTRVVKDKMSKRYADCVEAY IGALVIDRFGTEFLDIKEWLEELSEKKLAKSS Description Functional site 1) chain A residue 147 type sequence E description BINDING SITE FOR RESIDUE MG A 1 source : AC1 2) chain A residue 217 type sequence K description BINDING SITE FOR RESIDUE MG A 1 source : AC1 3) chain A residue 221 type sequence D description BINDING SITE FOR RESIDUE MG A 1 source : AC1 4) chain A residue 224 type sequence E description BINDING SITE FOR RESIDUE MG A 1 source : AC1 5) chain B residue 147 type sequence E description BINDING SITE FOR RESIDUE MG B 3 source : AC2 6) chain B residue 221 type sequence D description BINDING SITE FOR RESIDUE MG B 3 source : AC2 7) chain B residue 224 type sequence E description BINDING SITE FOR RESIDUE MG B 3 source : AC2 8) chain C residue 147 type sequence E description BINDING SITE FOR RESIDUE MG C 4 source : AC3 9) chain C residue 221 type sequence D description BINDING SITE FOR RESIDUE MG C 4 source : AC3 10) chain C residue 224 type sequence E description BINDING SITE FOR RESIDUE MG C 4 source : AC3 11) chain D residue 147 type sequence E description BINDING SITE FOR RESIDUE MG D 2 source : AC4 12) chain D residue 221 type sequence D description BINDING SITE FOR RESIDUE MG D 2 source : AC4 13) chain D residue 224 type sequence E description BINDING SITE FOR RESIDUE MG D 2 source : AC4 14) chain A residue 144-152 type prosite sequence ERLEFLGDS description RNASE_3_1 Ribonuclease III family signature. ERLEFLGDS source prosite : PS00517

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