|
|
eF-site ID
|
3rov-H |
|
PDB Code
|
3rov |
|
Chain
|
H |
|
click to enlarge
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Title
|
Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus |
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Classification
|
HORMONE |
|
Compound
|
Insulin |
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Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
|
Sequence
|
H: |
FVNQHLCGSHLVEALYLVCXERXFFYTKPT
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
H |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN D 31
|
| source |
: AC5
|
|
|
2)
|
chain |
H |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE IPH G 22
|
| source |
: AC7
|
|
|
3)
|
chain |
H |
| residue |
14 |
| type |
|
| sequence |
A
|
| description |
BINDING SITE FOR RESIDUE IPH G 22
|
| source |
: AC7
|
|
|
4)
|
chain |
H |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE CL H 31
|
| source |
: AC8
|
|
|
5)
|
chain |
H |
| residue |
5 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE IPH K 22
|
| source |
: BC1
|
|
|
|