eF-site ID 3rf3-ABCD PDB Code 3rf3 Chain A, B, C, D click to enlarge Title Shigella IpaA-VBS3 in complex with human vinculin Classification protein binding/toxin Compound Vinculin Source Homo sapiens (Human) (IPAA_SHIFL) Sequence A:  PVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLT APVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKV ENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSD LLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYT KNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEI NEIIRVLQLTSWDEDAW B:  MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDL TAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIK VENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTS DLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTY TKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKE LLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAW C:  TRETIFEASKKVTNSLSNLISLI D:  TRETIFEASKKVTNSLSNLISLIG Description Functional site 1) chain A residue 176 type sequence D description BINDING SITE FOR RESIDUE CAC A 300 source : AC1 2) chain A residue 199 type sequence K description BINDING SITE FOR RESIDUE CAC A 300 source : AC1 3) chain B residue 176 type sequence D description BINDING SITE FOR RESIDUE CAC B 300 source : AC2 4) chain B residue 199 type sequence K description BINDING SITE FOR RESIDUE CAC B 300 source : AC2 5) chain A residue 97 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P85972 source Swiss-Prot : SWS_FT_FI1 6) chain B residue 97 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P85972 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 173 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 8) chain B residue 173 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 9) chain A residue 162-182 type prosite sequence KNLGPGMTKMAKMIDERQQEL description VINCULIN_1 Vinculin family talin-binding region signature. KnLgpgMtkMakmideRQQEL source prosite : PS00663

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