eF-site/Summary 3r93-F

eF-site ID	3r93-F
PDB Code	3r93
Chain	F

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Title	Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide
Classification	CELL CYCLE
Compound	M-phase phosphoprotein 8
Source	Homo sapiens (Human) (3R93)

Sequence	F:	RTKQTARXSTGGKA

Description

Functional site


1)	chain	F
	residue	6
	type	MOD_RES
	sequence	T
	description	Phosphothreonine; by PKC => ECO:0000269\|PubMed:20228790
	source	Swiss-Prot : SWS_FT_FI5

2)	chain	F
	residue	8
	type	MOD_RES
	sequence	R
	description	Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250\|UniProtKB:P84228
	source	Swiss-Prot : SWS_FT_FI6

3)	chain	F
	residue	2
	type	MOD_RES
	sequence	R
	description	Citrulline; alternate => ECO:0000269\|PubMed:16567635
	source	Swiss-Prot : SWS_FT_FI1

4)	chain	F
	residue	3
	type	MOD_RES
	sequence	T
	description	Phosphothreonine; by HASPIN => ECO:0000269\|PubMed:15681610, ECO:0000269\|PubMed:16185088
	source	Swiss-Prot : SWS_FT_FI2

5)	chain	F
	residue	14
	type	MOD_RES
	sequence	K
	description	N6-succinyllysine; alternate => ECO:0000269\|PubMed:22389435
	source	Swiss-Prot : SWS_FT_FI10

6)	chain	F
	residue	4
	type	MOD_RES
	sequence	K
	description	N6-methyllysine; alternate => ECO:0000269\|PubMed:16267050, ECO:0000269\|PubMed:17194708
	source	Swiss-Prot : SWS_FT_FI3

7)	chain	F
	residue	5
	type	MOD_RES
	sequence	Q
	description	5-glutamyl serotonin; alternate => ECO:0000269\|PubMed:30867594
	source	Swiss-Prot : SWS_FT_FI4

8)	chain	F
	residue	9
	type	MOD_RES
	sequence	X
	description	N6-methyllysine; alternate => ECO:0000269\|PubMed:11242053, ECO:0000269\|PubMed:16185088, ECO:0000269\|PubMed:16267050, ECO:0000269\|PubMed:17194708
	source	Swiss-Prot : SWS_FT_FI7

9)	chain	F
	residue	10
	type	MOD_RES
	sequence	S
	description	Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269\|PubMed:10464286, ECO:0000269\|PubMed:11856369, ECO:0000269\|PubMed:12560483, ECO:0000269\|PubMed:15681610, ECO:0000269\|PubMed:16185088
	source	Swiss-Prot : SWS_FT_FI8

10)	chain	F
	residue	11
	type	MOD_RES
	sequence	T
	description	Phosphothreonine; by PKC => ECO:0000269\|PubMed:12560483, ECO:0000269\|PubMed:18066052, ECO:0000269\|PubMed:22901803
	source	Swiss-Prot : SWS_FT_FI9