eF-site ID 3r3e-A PDB Code 3r3e Chain A click to enlarge Title The glutathione bound structure of YqjG, a glutathione transferase homolog from Escherichia coli K-12 Classification TRANSFERASE Compound Uncharacterized protein yqjG Source Escherichia coli (strain K12) (YQJG_ECOLI) Sequence A:  GQLIDGVWHAFRNWLTADGAPGPTGTGGFIAEKDRYHLYV SLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFD DSFPGATGDTLYQNEFLYQLYLHADPHYSGRVTVPVLWDK KNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKI DELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLAR LEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKC DKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRS HKTINPTGIISIGPWQDLDEPHGRDVRF Description Functional site 1) chain A residue 63 type sequence C description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 2) chain A residue 65 type sequence W description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 3) chain A residue 96 type sequence W description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 4) chain A residue 130 type sequence R description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 5) chain A residue 132 type sequence T description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 6) chain A residue 133 type sequence V description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 7) chain A residue 134 type sequence P description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 8) chain A residue 148 type sequence E description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 9) chain A residue 149 type sequence S description BINDING SITE FOR RESIDUE GSH A 400 source : AC1 10) chain A residue 73 type sequence R description BINDING SITE FOR RESIDUE SO4 A 329 source : AC2 11) chain A residue 74 type sequence K description BINDING SITE FOR RESIDUE SO4 A 329 source : AC2 12) chain A residue 65 type sequence W description BINDING SITE FOR RESIDUE SO4 A 330 source : AC3 13) chain A residue 68 type sequence R description BINDING SITE FOR RESIDUE SO4 A 330 source : AC3 14) chain A residue 148 type sequence E description BINDING SITE FOR RESIDUE SO4 A 330 source : AC3 15) chain A residue 150 type sequence A description BINDING SITE FOR RESIDUE SO4 A 330 source : AC3 16) chain A residue 187 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 330 source : AC3 17) chain A residue 241 type sequence R description BINDING SITE FOR RESIDUE SO4 A 330 source : AC3 18) chain A residue 35 type sequence T description BINDING SITE FOR RESIDUE SO4 A 331 source : AC4 19) chain A residue 36 type sequence A description BINDING SITE FOR RESIDUE SO4 A 331 source : AC4 20) chain A residue 158 type sequence T description BINDING SITE FOR RESIDUE SO4 A 331 source : AC4 21) chain A residue 159 type sequence A description BINDING SITE FOR RESIDUE SO4 A 331 source : AC4 22) chain A residue 261 type sequence K description BINDING SITE FOR RESIDUE SO4 A 332 source : AC5 23) chain A residue 262 type sequence H description BINDING SITE FOR RESIDUE SO4 A 332 source : AC5 24) chain A residue 262 type sequence H description BINDING SITE FOR RESIDUE SO4 A 333 source : AC6 25) chain A residue 266 type sequence D description BINDING SITE FOR RESIDUE SO4 A 333 source : AC6 26) chain A residue 267 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 333 source : AC6 27) chain A residue 168 type sequence G description BINDING SITE FOR RESIDUE SO4 A 334 source : AC7 28) chain A residue 169 type sequence D description BINDING SITE FOR RESIDUE SO4 A 334 source : AC7 29) chain A residue 234 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 334 source : AC7 30) chain A residue 63 type ACT_SITE sequence C description Nucleophile => ECO:0000269|PubMed:22955277 source Swiss-Prot : SWS_FT_FI1 31) chain A residue 195 type ACT_SITE sequence Y description Proton donor/acceptor => ECO:0000305|PubMed:22955277 source Swiss-Prot : SWS_FT_FI2 32) chain A residue 148 type BINDING sequence E description BINDING => ECO:0000269|PubMed:22955277, ECO:0000269|Ref.5 source Swiss-Prot : SWS_FT_FI3 33) chain A residue 96 type BINDING sequence W description BINDING => ECO:0000269|PubMed:22955277, ECO:0000269|Ref.5 source Swiss-Prot : SWS_FT_FI3 34) chain A residue 130 type BINDING sequence R description BINDING => ECO:0000269|PubMed:22955277, ECO:0000269|Ref.5 source Swiss-Prot : SWS_FT_FI3 35) chain A residue 253 type SITE sequence Y description Lowers pKa of active site Cys => ECO:0000305 source Swiss-Prot : SWS_FT_FI4 36) chain A residue 296 type SITE sequence Y description Lowers pKa of active site Cys => ECO:0000305 source Swiss-Prot : SWS_FT_FI4

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