eF-site ID 3r2a-A PDB Code 3r2a Chain A click to enlarge Title Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein Classification TRANSCRIPTION Compound Retinoic acid receptor RXR-alpha Source null (NCOR2_HUMAN) Sequence A:  ANEDMPVERILEAELAVEPKDPVTNICQAADKQLFTLVEW AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKD GILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQM DKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEA YCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI GDTPIDTFLME Description Functional site 1) chain A residue 268 type sequence I description BINDING SITE FOR RESIDUE RHN A 1 source : AC1 2) chain A residue 306 type sequence N description BINDING SITE FOR RESIDUE RHN A 1 source : AC1 3) chain A residue 313 type sequence F description BINDING SITE FOR RESIDUE RHN A 1 source : AC1 4) chain A residue 324 type sequence I description BINDING SITE FOR RESIDUE RHN A 1 source : AC1 5) chain A residue 432 type sequence C description BINDING SITE FOR RESIDUE RHN A 1 source : AC1 6) chain A residue 436 type sequence L description BINDING SITE FOR RESIDUE RHN A 1 source : AC1 7) chain A residue 327 type BINDING sequence A description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1 8) chain A residue 316 type BINDING sequence R description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1

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