eF-site ID 3qzq-A PDB Code 3qzq Chain A click to enlarge Title Human enterovirus 71 3C protease mutant E71D in complex with rupintrivir Classification HYDROLASE/HYDROLASE INHIBITOR Compound 3C protein Source null (E7E815_9ENTO) Sequence A:  DFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPG KTIWIEHKLVNVLDAVELVDEQGVNLDLTLITLDTNEKFR DITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGF LNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGG NGRQGFCAGLKRSYFA Description Functional site 1) chain A residue 39 type sequence R description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 2) chain A residue 40 type sequence H description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 3) chain A residue 126 type sequence N description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 4) chain A residue 127 type sequence L description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 5) chain A residue 128 type sequence S description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 6) chain A residue 130 type sequence K description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 7) chain A residue 142 type sequence T description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 8) chain A residue 143 type sequence K description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 9) chain A residue 144 type sequence A description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 10) chain A residue 145 type sequence G description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 11) chain A residue 147 type sequence C description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 12) chain A residue 161 type sequence H description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 13) chain A residue 162 type sequence I description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 14) chain A residue 163 type sequence G description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 15) chain A residue 164 type sequence G description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 16) chain A residue 165 type sequence N description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 17) chain A residue 170 type sequence F description BINDING SITE FOR RESIDUE AG7 A 501 source : AC1 18) chain A residue 53 type sequence L description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2

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