eF-site ID 3qzq-B PDB Code 3qzq Chain B click to enlarge Title Human enterovirus 71 3C protease mutant E71D in complex with rupintrivir Classification HYDROLASE/HYDROLASE INHIBITOR Compound 3C protein Source null (E7E815_9ENTO) Sequence B:  FALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGK TIWIEHKLVNVLDAVELVDEQGVNLDLTLITLDTNEKFRD ITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFL NLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGN GRQGFCAGLKRSYFAS Description Functional site 1) chain B residue 39 type sequence R description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 2) chain B residue 40 type sequence H description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 3) chain B residue 122 type sequence Y description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 4) chain B residue 125 type sequence L description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 5) chain B residue 126 type sequence N description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 6) chain B residue 127 type sequence L description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 7) chain B residue 128 type sequence S description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 8) chain B residue 130 type sequence K description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 9) chain B residue 142 type sequence T description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 10) chain B residue 143 type sequence K description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 11) chain B residue 144 type sequence A description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 12) chain B residue 145 type sequence G description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 13) chain B residue 147 type sequence C description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 14) chain B residue 161 type sequence H description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 15) chain B residue 162 type sequence I description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 16) chain B residue 163 type sequence G description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 17) chain B residue 164 type sequence G description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 18) chain B residue 165 type sequence N description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2 19) chain B residue 170 type sequence F description BINDING SITE FOR RESIDUE AG7 B 501 source : AC2

Display surface Download Links