eF-site ID 3qy7-A PDB Code 3qy7 Chain A click to enlarge Title Crystal structures of YwqE from Bacillus subtilis and CpsB from Streptococcus pneumoniae, unique metal-dependent tyrosine phosphatases Classification HYDROLASE Compound Tyrosine-protein phosphatase YwqE Source Bacillus subtilis (YWQE_BACSU) Sequence A:  MIDIHCHILPAMDDGAGDSADSIEMARAAVRQGIRTIIAT PHHNNGVYKNEPAAVREAADQLNKRLIKEDIPLHVLPGQE IRIYGEVEQDLAKRQLLSLNDTKYILIEFPFDHVPRYAEQ LFYDLQLKGYIPVIAHPERNREIRENPSLLYHLVEKGAAS QITSGSLAGIFGKQLKAFSLRLVEANLIHFVASDAHNVKT RNFHTQEALYVLEKEFGSELPYMLTENAELLLRNQTIFRQ PPQPVKR Description Functional site 1) chain A residue 80 type sequence E description BINDING SITE FOR RESIDUE FE A 263 source : AC1 2) chain A residue 108 type sequence E description BINDING SITE FOR RESIDUE FE A 263 source : AC1 3) chain A residue 136 type sequence H description BINDING SITE FOR RESIDUE FE A 263 source : AC1 4) chain A residue 5 type sequence H description BINDING SITE FOR RESIDUE FE A 264 source : AC2 5) chain A residue 7 type sequence H description BINDING SITE FOR RESIDUE FE A 264 source : AC2 6) chain A residue 80 type sequence E description BINDING SITE FOR RESIDUE FE A 264 source : AC2 7) chain A residue 194 type sequence D description BINDING SITE FOR RESIDUE FE A 264 source : AC2 8) chain A residue 14 type sequence D description BINDING SITE FOR RESIDUE MG A 265 source : AC3 9) chain A residue 42 type sequence H description BINDING SITE FOR RESIDUE MG A 265 source : AC3 10) chain A residue 196 type sequence H description BINDING SITE FOR RESIDUE MG A 265 source : AC3 11) chain A residue 7 type sequence H description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4 12) chain A residue 14 type sequence D description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4 13) chain A residue 42 type sequence H description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4 14) chain A residue 80 type sequence E description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4 15) chain A residue 108 type sequence E description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4 16) chain A residue 194 type sequence D description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4 17) chain A residue 196 type sequence H description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4 18) chain A residue 201 type sequence R description BINDING SITE FOR RESIDUE PO4 A 266 source : AC4

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