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|
eF-site ID
|
3q2p-ABCD |
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PDB Code
|
3q2p |
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Chain
|
A, B, C, D |
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click to enlarge
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Title
|
Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix |
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Classification
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PLANT PROTEIN |
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Compound
|
Monellin chain B/Monellin chain A chimeric protein |
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Source
|
Dioscoreophyllum cumminsii (Serendipity berry) (Rhopalandria cumminsii) (MONA_DIOCU) |
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Sequence
|
A: |
GEWEIIDIGPFTQNLAKFAVDEENKIGQYGRLTFNKAIRP
CMKKTIYENEGFREIKGYEYQLYVYASDKLFRADISEDYK
TRGRKLLRFNGPVPPP
|
| B: |
MGEWEIIDIGPFTQNLAKFAVDEENKIGQYGRLTFNKAIR
PCMKKTIYENEGFREIKGYEYQLYVYASDKLFRADISEDY
KTRGRKLLRFNGPVPPP
|
| C: |
GEWEIIDIGPFTQNLAKFAVDEENKIGQYGRLTFNKAIRP
CMKKTIYENEGFREIKGYEYQLYVYASDKLFRADISEDYK
TRGRKLLRFNGPVPPP
|
| D: |
GEWEIIDIGPFTQNLAKFAVDEENKIGQYGRLTFNKAIRP
CMKKTIYENEGFREIKGYEYQLYVYASDKLFRADISEDYK
TRGRKLLRFNGPVPPP
|
|
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
41 |
| type |
SITE |
| sequence |
C
|
| description |
Blocking, abolishes the sweet taste
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
41 |
| type |
SITE |
| sequence |
C
|
| description |
Blocking, abolishes the sweet taste
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
C |
| residue |
41 |
| type |
SITE |
| sequence |
C
|
| description |
Blocking, abolishes the sweet taste
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
D |
| residue |
41 |
| type |
SITE |
| sequence |
C
|
| description |
Blocking, abolishes the sweet taste
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|