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eF-site ID
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3q25-A |
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PDB Code
|
3q25 |
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Chain
|
A |
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click to enlarge
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Title
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Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) |
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Classification
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SUGAR BINDING PROTEIN, PROTEIN FIBRIL |
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Compound
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Maltose-binding periplasmic protein/alpha-synuclein chimeric protein |
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Source
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(SYUA_HUMAN) |
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Sequence
|
A: |
IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPD
KLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITP
DKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDL
LPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLI
AADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKN
KHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVN
YGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLE
NYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATM
ENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEAL
KDAQTNSSSMDVFMKGLSKAKEGVVAAA
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Description
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Functional site
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1)
|
chain |
A |
| residue |
108-125 |
| type |
prosite |
| sequence |
PIAVEALSLIYNKDLLPN
|
| description |
SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN
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| source |
prosite : PS01037
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2)
|
chain |
A |
| residue |
373 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
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|
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3)
|
chain |
A |
| residue |
372 |
| type |
MOD_RES |
| sequence |
M
|
| description |
N-acetylmethionine => ECO:0000269|PubMed:22407793
|
| source |
Swiss-Prot : SWS_FT_FI2
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