eF-site ID 3q24-B PDB Code 3q24 Chain B click to enlarge Title X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with pppGpG and pyrophosphate: product complex Classification TRANSFERASE/DNA/RNA Compound Virion RNA polymerase Source (3Q24) Sequence B:  TEELKEGIDAVYPSLVGTADSKAEGIKNYFKLSFTLPEEQ KSRTVGSEAPLKDVAQALSSRARYELFTEKETANPAFNGE VIKRYKELMEHGEGIADILRSRLAKFLNTKDVGKRFAQGT EANRWVGGKLLNIVEQDGDTFKYNEQLLQTAVLAGLQWRL TATSNTAIKDAKDVAAITGIDQALLPEGLVEQFDTGMTLT EAVSSLAQKIESYWGLSRNPNAPLGYTKGIPTAMAAEILA AFVESTDVVENIVDMSEIDPDNKKTIGLYTITELDSFDPI NSFPTAIEEAVLVNPTEKMFFGDDIPPVANTQLRNPAVRN TPEQKAALKAEQATEFYVHTPMVQFYETLGKDRILELMGA GTLNKELLNDNHAKSLEGKNRSVEDSYNQLFSVIEQVRAQ SEDISTVPIHYAYNMTRVGRMQMLGKYNPQSAKLVREAIL PTKATLDLSNQNNEDFSAFQLGLAQALDIKVHTMTREVMS DELTKLLEGNLKPAIDMMVEFNTTGSLPENAVDVLNTALG DRKSFVALMALMEYSRYLVAEDKSAFVTPLYVEADGVTNG PINAMMLMTGGLFTPDWIRNIAKGGLFIGSPNKTMNEHRS TADNNDLYQASTNALMESLGKLRSNYASNMPIQSQIDSLL SLMDLFLPDINLGENGALELKRGIAKNPLTITIYGSGARG IAGKLVSSVTDAIYERMSDVLKARAKDPNISAAMAMFGKQ AASEAHAEELLARFLKDMETLTSTVPVKRKGVLELQSTGT GAKGKINPKTYTIKGEQLKALQENMLHFFVEPLRNGITQT VGESLVYSTEQLQKATQIQSVVLEDMFKQRVQEKLAEKAK DPTWKKGDFLTQKELNDIQASLNNLAPMIETGSQTFYIAG SENAEVANQVLATNLDDRMRVPMSIYAPAQAGVAGIPFMT IGTGDGMMMQTLSTMKGAPKNTLKIFDGMNIGLNDITDAS RKANEAVYTSWQGNPIKNVYESYAKFMKNVDFSKLSPEAL EAIGKSALEYDQRENATVDDIANAASLIERNLRNIALGVD IRHKVLDKVNLSIDQMAAVGAPYQNNGKIDLSNMTPEQQA DELNKLFREELEAR Description Functional site 1) chain B residue 469 type sequence Q description BINDING SITE FOR RESIDUE 2HP B 1106 source : AC5 2) chain B residue 473 type sequence I description BINDING SITE FOR RESIDUE 2HP B 1106 source : AC5 3) chain B residue 474 type sequence K description BINDING SITE FOR RESIDUE 2HP B 1106 source : AC5 4) chain B residue 475 type sequence V description BINDING SITE FOR RESIDUE 2HP B 1106 source : AC5 5) chain B residue 476 type sequence H description BINDING SITE FOR RESIDUE 2HP B 1106 source : AC5 6) chain B residue 476 type sequence H description BINDING SITE FOR RESIDUE POP B 1107 source : AC6 7) chain B residue 560 type sequence G description BINDING SITE FOR RESIDUE POP B 1107 source : AC6 8) chain B residue 561 type sequence V description BINDING SITE FOR RESIDUE POP B 1107 source : AC6 9) chain B residue 562 type sequence T description BINDING SITE FOR RESIDUE POP B 1107 source : AC6 10) chain B residue 610 type sequence D description BINDING SITE FOR RESIDUE POP B 1107 source : AC6 11) chain B residue 612 type sequence Y description BINDING SITE FOR RESIDUE POP B 1107 source : AC6 12) chain B residue 666 type sequence R description BINDING SITE FOR RESIDUE POP B 1107 source : AC6 13) chain B residue 437 type BINDING sequence K description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1 14) chain B residue 559 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 670 type BINDING sequence K description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 951 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1

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