eF-site ID 3q23-A PDB Code 3q23 Chain A click to enlarge Title X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II Classification TRANSFERASE/DNA Compound Virion RNA polymerase Source (3Q23) Sequence A:  EELKEGIDAVYPSLVGTADSKAEGIKNYFKLSFTLPEEQK SRTVGSEAPLKDVAQALSSRARYELFTEKETANPAFNGEV IKRYKELMEHGEGIADILRSRLAKFLNTKDVGKRFAQGTE ANRWVGGKLLNIVEQDGDTFKYNEQLLQTAVLAGLQWRLT ATSNTAIKDAKDVAAITGIDQALLPEGLVEQFDTGMTLTE AVSSLAQKIESYWGLSRNPNAPLGYTKGIPTAMAAEILAA FVESTDVVENIVDMSEIDPDNKKTIGLYTITELDSFDPIN SFPTAIEEAVLVNPTEKMFFGDDIPPVANTQLRNPAVRNT PEQKAALKAEQATEFYVHTPMVQFYETLGKDRILELMGAG TLNKELLNDNHAKSLEGKNRSVEDSYNQLFSVIEQVRAQS EDISTVPIHYAYNMTRVGRMQMLGKYNPQSAKLVREAILP TKATLDLSNQNNEDFSAFQLGLAQALDIKVHTMTREVMSD ELTKLLEGNLKPAIDMMVEFNTTGSLPENAVDVLNTALGD RKSFVALMALMEYSRYLVAEDKSAFVTPLYVEADGVTNGP INAMMLMTGGLFTPDWIRNIAKGGLFIGSPNKTMNEHRST ADNNDLYQASTNALMESLGKLRSNYASNMPIQSQIDSLLS LMDLFLPDINLGENGALELKRGIAKNPLTITIYGSGARGI AGKLVSSVTDAIYERMSDVLKARAKDPNISAAMAMFGKQA ASEAHAEELLARFLKDMETLTSTVPVKRKGVLELQSTGTG AKGKINPKTYTIKGEQLKALQENMLHFFVEPLRNGITQTV GESLVYSTEQLQKATQIQSVVLEDMFKQRVQEKLAEKAKD PTWKKGDFLTQKELNDIQASLNNLAPMIETGSQTFYIAGS ENAEVANQVLATNLDDRMRVPMSIYAPAQAGVAGIPFMTI GTGDGMMMQTLSTMKGAPKNTLKIFDGMNIGLNDITDASR KANEAVYTSWQGNPIKNVYESYAKFMKNVDFSKLSPEALE AIGKSALEYDQRENATVDDIANAASLIERNLRNIALGVDI RHKVLDKVNLSIDQMAAVGAPYQNNGKIDLSNMTPEQQAD ELNKLFREELEARKQ Description Functional site 1) chain A residue 424 type sequence R description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 2) chain A residue 559 type sequence D description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 3) chain A residue 560 type sequence G description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 4) chain A residue 561 type sequence V description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 5) chain A residue 562 type sequence T description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 6) chain A residue 563 type sequence N description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 7) chain A residue 564 type sequence G description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 8) chain A residue 565 type sequence P description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 9) chain A residue 612 type sequence Y description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 10) chain A residue 666 type sequence R description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 11) chain A residue 670 type sequence K description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 12) chain A residue 671 type sequence N description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 13) chain A residue 678 type sequence Y description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 14) chain A residue 951 type sequence D description BINDING SITE FOR RESIDUE G2P A 1108 source : AC1 15) chain A residue 559 type sequence D description BINDING SITE FOR RESIDUE MN A 1107 source : AC2 16) chain A residue 951 type sequence D description BINDING SITE FOR RESIDUE MN A 1107 source : AC2 17) chain A residue 559 type sequence D description BINDING SITE FOR RESIDUE MN A 1109 source : AC3 18) chain A residue 560 type sequence G description BINDING SITE FOR RESIDUE MN A 1109 source : AC3 19) chain A residue 951 type sequence D description BINDING SITE FOR RESIDUE MN A 1109 source : AC3 20) chain A residue 469 type sequence Q description BINDING SITE FOR RESIDUE 2HP A 1110 source : AC4 21) chain A residue 473 type sequence I description BINDING SITE FOR RESIDUE 2HP A 1110 source : AC4 22) chain A residue 474 type sequence K description BINDING SITE FOR RESIDUE 2HP A 1110 source : AC4 23) chain A residue 475 type sequence V description BINDING SITE FOR RESIDUE 2HP A 1110 source : AC4 24) chain A residue 476 type sequence H description BINDING SITE FOR RESIDUE 2HP A 1110 source : AC4 25) chain A residue 424 type sequence R description BINDING SITE FOR RESIDUE G2P A 1111 source : AC5 26) chain A residue 437 type sequence K description BINDING SITE FOR RESIDUE G2P A 1111 source : AC5 27) chain A residue 557 type sequence E description BINDING SITE FOR RESIDUE G2P A 1111 source : AC5 28) chain A residue 559 type sequence D description BINDING SITE FOR RESIDUE G2P A 1111 source : AC5 29) chain A residue 925 type sequence I description BINDING SITE FOR RESIDUE G2P A 1111 source : AC5 30) chain A residue 950 type sequence F description BINDING SITE FOR RESIDUE G2P A 1111 source : AC5 31) chain A residue 951 type sequence D description BINDING SITE FOR RESIDUE G2P A 1111 source : AC5 32) chain A residue 437 type BINDING sequence K description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1 33) chain A residue 559 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1 34) chain A residue 670 type BINDING sequence K description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1 35) chain A residue 951 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21321236, ECO:0000269|PubMed:23235152 source Swiss-Prot : SWS_FT_FI1

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