eF-site ID 3pxm-AB
PDB Code 3pxm
Chain A, B

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Title Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix
Classification PLANT PROTEIN
Compound Monellin chain B/Monellin chain A chimeric protein
Source Dioscoreophyllum cumminsii (Serendipity berry) (Rhopalandria cumminsii) (MONA_DIOCU)
Sequence A:  GEWEIIDIGPFTQNLGKFAVDEENKIGQYGRLTFNKAIRP
CMKKTIYENEGFREIKGYEYQLYVYASDKLFRADISEDYK
TRGRKLLRFNGPVPPP
B:  GEWEIIDIGPFTQNLGKFAVDEENKIGQYGRLTFNKAIRP
CMKKTIYENEGFREIKGYEYQLYVYASDKLFRADISEDYK
TRGRKLLRFNGPVPPP
Description


Functional site

1) chain A
residue 41
type SITE
sequence C
description Blocking, abolishes the sweet taste
source Swiss-Prot : SWS_FT_FI1

2) chain B
residue 41
type SITE
sequence C
description Blocking, abolishes the sweet taste
source Swiss-Prot : SWS_FT_FI1


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