|
|
eF-site ID
|
3pxc-X |
|
PDB Code
|
3pxc |
|
Chain
|
X |
|
click to enlarge
|
|
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Title
|
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: R1699Q |
|
Classification
|
PROTEIN BINDING |
|
Compound
|
Breast cancer type 1 susceptibility protein |
|
Source
|
Homo sapiens (Human) (BRCA1_HUMAN) |
|
|
Sequence
|
X: |
RMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVV
MKTDAFVCEQTLKYFLGIAGGKWVVSYFWVTQSIKERKML
NEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCY
GPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVV
VQPDAWTFHAIGQMCEAPVVTREWVLDSVALYQCQELDTY
LIPQIP
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
X |
| residue |
1655 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE SO4 X 20
|
| source |
: AC1
|
|
|
2)
|
chain |
X |
| residue |
1656 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE SO4 X 20
|
| source |
: AC1
|
|
|
3)
|
chain |
X |
| residue |
1702 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SO4 X 20
|
| source |
: AC1
|
|
|
4)
|
chain |
X |
| residue |
1673 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE NI X 21
|
| source |
: AC2
|
|
|
5)
|
chain |
X |
| residue |
1805 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE NI X 21
|
| source |
: AC2
|
|
|
|