eF-site ID 3pu3-AB PDB Code 3pu3 Chain A, B click to enlarge Title PHF2 Jumonji domain-NOG complex Classification PROTEIN BINDING Compound PHD finger protein 2 Source Homo sapiens (Human) (PHF2_HUMAN) Sequence A:  KPVQNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYME EHGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSV DVTDVTKQKDCKMKLKEFVDYYYSTNRKRVLNVTNLEFSD TRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLI CVKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANIS LYERWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIPSGW IYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGS LTQFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGA KILNGAFRSWTKKLAEHEDELPEHFKPSQLIKDLAKEIRL SEN B:  QNGSQLFIKELRSRTFPSAEDVVARVPGSQLTLGYMEEHG FTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVT DVTKQKDCKMKLKEFVDYYYSTNRKRVLNVTNLEFSDTRM SSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLICVK DSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYE RWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIPSGWIYA TLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQ FPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKIL NGAFRSWTKKQAAEHEDELPEHFKPSQLIKDLAKEIRLSE N Description Functional site 1) chain A residue 193 type sequence T description BINDING SITE FOR RESIDUE OGA A 1 source : AC1 2) chain A residue 246 type sequence T description BINDING SITE FOR RESIDUE OGA A 1 source : AC1 3) chain A residue 249 type sequence H description BINDING SITE FOR RESIDUE OGA A 1 source : AC1 4) chain A residue 251 type sequence D description BINDING SITE FOR RESIDUE OGA A 1 source : AC1 5) chain A residue 259 type sequence Y description BINDING SITE FOR RESIDUE OGA A 1 source : AC1 6) chain A residue 323 type sequence T description BINDING SITE FOR RESIDUE OGA A 1 source : AC1 7) chain A residue 335 type sequence H description BINDING SITE FOR RESIDUE OGA A 1 source : AC1 8) chain B residue 193 type sequence T description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 9) chain B residue 238 type sequence L description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 10) chain B residue 240 type sequence C description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 11) chain B residue 246 type sequence T description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 12) chain B residue 249 type sequence H description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 13) chain B residue 251 type sequence D description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 14) chain B residue 259 type sequence Y description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 15) chain B residue 266 type sequence K description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 16) chain B residue 321 type sequence Y description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 17) chain B residue 323 type sequence T description BINDING SITE FOR RESIDUE OGA B 2 source : AC2 18) chain B residue 317 type sequence S description BINDING SITE FOR RESIDUE EDO B 1 source : AC3 19) chain B residue 341 type sequence S description BINDING SITE FOR RESIDUE EDO B 1 source : AC3 20) chain B residue 339 type sequence S description BINDING SITE FOR RESIDUE EDO B 452 source : AC4 21) chain B residue 340 type sequence L description BINDING SITE FOR RESIDUE EDO B 452 source : AC4 22) chain B residue 341 type sequence S description BINDING SITE FOR RESIDUE EDO B 452 source : AC4 23) chain B residue 342 type sequence V description BINDING SITE FOR RESIDUE EDO B 452 source : AC4 24) chain B residue 343 type sequence E description BINDING SITE FOR RESIDUE EDO B 452 source : AC4 25) chain B residue 394 type sequence H description BINDING SITE FOR RESIDUE EDO B 452 source : AC4 26) chain B residue 401 type sequence I description BINDING SITE FOR RESIDUE EDO B 452 source : AC4 27) chain B residue 343 type sequence E description BINDING SITE FOR RESIDUE EDO B 4 source : AC5 28) chain A residue 214 type sequence K description BINDING SITE FOR RESIDUE EDO A 5 source : AC6 29) chain A residue 215 type sequence L description BINDING SITE FOR RESIDUE EDO A 5 source : AC6 30) chain A residue 217 type sequence W description BINDING SITE FOR RESIDUE EDO A 5 source : AC6 31) chain A residue 220 type sequence N description BINDING SITE FOR RESIDUE EDO A 5 source : AC6 32) chain A residue 221 type sequence Y description BINDING SITE FOR RESIDUE EDO A 5 source : AC6 33) chain A residue 339 type sequence S description BINDING SITE FOR RESIDUE EDO A 5 source : AC6 34) chain A residue 221 type sequence Y description BINDING SITE FOR RESIDUE EDO A 6 source : AC7 35) chain A residue 339 type sequence S description BINDING SITE FOR RESIDUE EDO A 6 source : AC7 36) chain A residue 373 type sequence M description BINDING SITE FOR RESIDUE EDO A 6 source : AC7 37) chain A residue 376 type sequence H description BINDING SITE FOR RESIDUE EDO A 6 source : AC7 38) chain A residue 395 type sequence L description BINDING SITE FOR RESIDUE EDO A 6 source : AC7 39) chain A residue 107 type sequence R description BINDING SITE FOR RESIDUE EDO B 7 source : AC8 40) chain A residue 130 type sequence P description BINDING SITE FOR RESIDUE EDO B 7 source : AC8 41) chain B residue 179 type sequence D description BINDING SITE FOR RESIDUE EDO B 7 source : AC8 42) chain B residue 182 type sequence Y description BINDING SITE FOR RESIDUE EDO B 7 source : AC8 43) chain A residue 375 type sequence K description BINDING SITE FOR RESIDUE EDO A 9 source : AC9 44) chain A residue 426 type sequence F description BINDING SITE FOR RESIDUE EDO A 9 source : AC9 45) chain A residue 427 type sequence K description BINDING SITE FOR RESIDUE EDO A 9 source : AC9 46) chain A residue 221 type sequence Y description BINDING SITE FOR RESIDUE EDO A 10 source : BC1 47) chain A residue 372 type sequence Y description BINDING SITE FOR RESIDUE EDO A 10 source : BC1 48) chain A residue 379 type sequence E description BINDING SITE FOR RESIDUE EDO A 10 source : BC1 49) chain A residue 208 type sequence P description BINDING SITE FOR RESIDUE EDO A 11 source : BC2 50) chain A residue 212 type sequence V description BINDING SITE FOR RESIDUE EDO A 11 source : BC2 51) chain A residue 234 type sequence T description BINDING SITE FOR RESIDUE EDO A 11 source : BC2 52) chain A residue 258 type sequence W description BINDING SITE FOR RESIDUE EDO A 11 source : BC2 53) chain A residue 334 type sequence G description BINDING SITE FOR RESIDUE EDO A 11 source : BC2 54) chain A residue 335 type sequence H description BINDING SITE FOR RESIDUE EDO A 11 source : BC2 55) chain A residue 198 type sequence S description BINDING SITE FOR RESIDUE GOL A 12 source : BC3 56) chain A residue 230 type sequence K description BINDING SITE FOR RESIDUE GOL A 12 source : BC3 57) chain A residue 231 type sequence P description BINDING SITE FOR RESIDUE GOL A 12 source : BC3 58) chain A residue 232 type sequence K description BINDING SITE FOR RESIDUE GOL A 12 source : BC3 59) chain A residue 234 type sequence T description BINDING SITE FOR RESIDUE GOL A 12 source : BC3 60) chain B residue 221 type sequence Y description BINDING SITE FOR RESIDUE EDO B 13 source : BC4 61) chain B residue 372 type sequence Y description BINDING SITE FOR RESIDUE EDO B 13 source : BC4 62) chain A residue 212 type sequence V description BINDING SITE FOR RESIDUE EDO A 16 source : BC6 63) chain A residue 213 type sequence K description BINDING SITE FOR RESIDUE EDO A 16 source : BC6 64) chain A residue 216 type sequence S description BINDING SITE FOR RESIDUE EDO A 16 source : BC6 65) chain A residue 219 type sequence E description BINDING SITE FOR RESIDUE EDO A 16 source : BC6 66) chain A residue 408 type sequence S description BINDING SITE FOR RESIDUE EDO A 17 source : BC7 67) chain A residue 418 type sequence H description BINDING SITE FOR RESIDUE EDO A 17 source : BC7 68) chain A residue 101 type sequence A description BINDING SITE FOR RESIDUE EDO A 18 source : BC8 69) chain A residue 102 type sequence E description BINDING SITE FOR RESIDUE EDO A 18 source : BC8 70) chain A residue 105 type sequence V description BINDING SITE FOR RESIDUE EDO A 18 source : BC8 71) chain A residue 107 type sequence R description BINDING SITE FOR RESIDUE EDO A 18 source : BC8 72) chain A residue 419 type sequence E description BINDING SITE FOR RESIDUE EDO A 19 source : BC9 73) chain A residue 422 type sequence L description BINDING SITE FOR RESIDUE EDO A 19 source : BC9 74) chain A residue 423 type sequence P description BINDING SITE FOR RESIDUE EDO A 19 source : BC9 75) chain A residue 424 type sequence E description BINDING SITE FOR RESIDUE EDO A 19 source : BC9 76) chain B residue 274 type sequence A description BINDING SITE FOR RESIDUE EDO A 19 source : BC9 77) chain B residue 276 type sequence A description BINDING SITE FOR RESIDUE EDO A 19 source : BC9 78) chain B residue 277 type sequence N description BINDING SITE FOR RESIDUE EDO A 19 source : BC9 79) chain A residue 220 type sequence N description BINDING SITE FOR RESIDUE EDO A 20 source : CC1 80) chain A residue 102 type sequence E description BINDING SITE FOR RESIDUE EDO B 21 source : CC2 81) chain B residue 145 type sequence Y description BINDING SITE FOR RESIDUE EDO B 21 source : CC2 82) chain B residue 146 type sequence V description BINDING SITE FOR RESIDUE EDO B 21 source : CC2 83) chain B residue 181 type sequence Y description BINDING SITE FOR RESIDUE EDO B 21 source : CC2 84) chain B residue 182 type sequence Y description BINDING SITE FOR RESIDUE EDO B 21 source : CC2 85) chain B residue 208 type sequence P description BINDING SITE FOR RESIDUE EDO B 22 source : CC3 86) chain B residue 233 type sequence V description BINDING SITE FOR RESIDUE EDO B 22 source : CC3 87) chain B residue 234 type sequence T description BINDING SITE FOR RESIDUE EDO B 22 source : CC3 88) chain B residue 258 type sequence W description BINDING SITE FOR RESIDUE EDO B 22 source : CC3 89) chain B residue 334 type sequence G description BINDING SITE FOR RESIDUE EDO B 22 source : CC3 90) chain B residue 335 type sequence H description BINDING SITE FOR RESIDUE EDO B 22 source : CC3 91) chain A residue 293 type sequence M description BINDING SITE FOR RESIDUE EDO A 23 source : CC4 92) chain A residue 294 type sequence F description BINDING SITE FOR RESIDUE EDO A 23 source : CC4 93) chain A residue 297 type sequence D description BINDING SITE FOR RESIDUE EDO A 23 source : CC4 94) chain A residue 298 type sequence Q description BINDING SITE FOR RESIDUE EDO A 23 source : CC4 95) chain A residue 218 type sequence V description BINDING SITE FOR RESIDUE EDO A 24 source : CC5 96) chain A residue 219 type sequence E description BINDING SITE FOR RESIDUE EDO A 24 source : CC5 97) chain A residue 230 type sequence K description BINDING SITE FOR RESIDUE EDO A 24 source : CC5 98) chain A residue 234 type sequence T description BINDING SITE FOR RESIDUE EDO A 24 source : CC5 99) chain A residue 249 type sequence H description BINDING SITE FOR RESIDUE EDO A 26 source : CC6 100) chain A residue 250 type sequence I description BINDING SITE FOR RESIDUE EDO A 26 source : CC6 101) chain A residue 361 type sequence T description BINDING SITE FOR RESIDUE EDO A 26 source : CC6 102) chain B residue 229 type sequence A description BINDING SITE FOR RESIDUE EDO B 28 source : CC7 103) chain B residue 365 type sequence N description BINDING SITE FOR RESIDUE EDO B 28 source : CC7 104) chain B residue 230 type sequence K description BINDING SITE FOR RESIDUE EDO B 29 source : CC8 105) chain B residue 232 type sequence K description BINDING SITE FOR RESIDUE EDO B 29 source : CC8 106) chain B residue 364 type sequence P description BINDING SITE FOR RESIDUE EDO B 29 source : CC8 107) chain B residue 404 type sequence G description BINDING SITE FOR RESIDUE EDO B 30 source : CC9 108) chain B residue 343 type sequence E description BINDING SITE FOR RESIDUE EDO B 31 source : DC1 109) chain B residue 344 type sequence M description BINDING SITE FOR RESIDUE EDO B 31 source : DC1 110) chain B residue 347 type sequence R description BINDING SITE FOR RESIDUE EDO B 31 source : DC1 111) chain A residue 119 type sequence E description BINDING SITE FOR RESIDUE EDO A 33 source : DC2 112) chain A residue 286 type sequence S description BINDING SITE FOR RESIDUE EDO A 34 source : DC3 113) chain A residue 355 type sequence L description BINDING SITE FOR RESIDUE EDO A 34 source : DC3 114) chain A residue 300 type sequence D description BINDING SITE FOR RESIDUE EDO A 35 source : DC4 115) chain B residue 427 type sequence K description BINDING SITE FOR RESIDUE EDO A 35 source : DC4 116) chain A residue 407 type sequence R description BINDING SITE FOR RESIDUE EDO A 36 source : DC5 117) chain A residue 201 type sequence R description BINDING SITE FOR RESIDUE EDO A 37 source : DC6 118) chain B residue 137 type sequence L description BINDING SITE FOR RESIDUE EDO B 38 source : DC7 119) chain B residue 210 type sequence D description BINDING SITE FOR RESIDUE EDO B 39 source : DC8 120) chain B residue 283 type sequence R description BINDING SITE FOR RESIDUE EDO B 41 source : EC1 121) chain B residue 284 type sequence W description BINDING SITE FOR RESIDUE EDO B 41 source : EC1 122) chain B residue 287 type sequence A description BINDING SITE FOR RESIDUE EDO B 41 source : EC1 123) chain B residue 293 type sequence M description BINDING SITE FOR RESIDUE EDO B 41 source : EC1 124) chain B residue 298 type sequence Q description BINDING SITE FOR RESIDUE EDO B 41 source : EC1 125) chain A residue 93 type sequence L description BINDING SITE FOR RESIDUE EDO A 42 source : EC2 126) chain A residue 94 type sequence R description BINDING SITE FOR RESIDUE EDO A 42 source : EC2 127) chain A residue 96 type sequence R description BINDING SITE FOR RESIDUE EDO A 42 source : EC2 128) chain A residue 98 type sequence F description BINDING SITE FOR RESIDUE EDO A 42 source : EC2 129) chain A residue 269 type sequence Y description BINDING SITE FOR RESIDUE EDO A 42 source : EC2 130) chain A residue 304 type sequence K description BINDING SITE FOR RESIDUE EDO A 42 source : EC2 131) chain B residue 280 type sequence L description BINDING SITE FOR RESIDUE EDO B 43 source : EC3 132) chain B residue 283 type sequence R description BINDING SITE FOR RESIDUE EDO B 43 source : EC3 133) chain B residue 284 type sequence W description BINDING SITE FOR RESIDUE EDO B 43 source : EC3 134) chain B residue 298 type sequence Q description BINDING SITE FOR RESIDUE EDO B 43 source : EC3 135) chain B residue 265 type sequence E description BINDING SITE FOR RESIDUE EDO B 44 source : EC4 136) chain B residue 115 type sequence L description BINDING SITE FOR RESIDUE EDO B 45 source : EC5 137) chain B residue 119 type sequence E description BINDING SITE FOR RESIDUE EDO B 45 source : EC5 138) chain B residue 394 type sequence H description BINDING SITE FOR RESIDUE EDO B 45 source : EC5 139) chain A residue 155 type sequence P description BINDING SITE FOR RESIDUE EDO A 46 source : EC6 140) chain A residue 156 type sequence E description BINDING SITE FOR RESIDUE EDO A 46 source : EC6 141) chain A residue 175 type sequence K description BINDING SITE FOR RESIDUE EDO A 46 source : EC6 142) chain B residue 308 type sequence K description BINDING SITE FOR RESIDUE EDO A 46 source : EC6 143) chain B residue 223 type sequence P description BINDING SITE FOR RESIDUE EDO B 47 source : EC7 144) chain B residue 225 type sequence D description BINDING SITE FOR RESIDUE EDO B 47 source : EC7 145) chain B residue 347 type sequence R description BINDING SITE FOR RESIDUE EDO B 48 source : EC8 146) chain B residue 350 type sequence E description BINDING SITE FOR RESIDUE EDO B 48 source : EC8 147) chain B residue 354 type sequence R description BINDING SITE FOR RESIDUE EDO B 48 source : EC8 148) chain B residue 193 type sequence T description BINDING SITE FOR RESIDUE EDO B 49 source : EC9 149) chain B residue 194 type sequence N description BINDING SITE FOR RESIDUE EDO B 49 source : EC9 150) chain B residue 236 type sequence Y description BINDING SITE FOR RESIDUE EDO B 49 source : EC9 151) chain B residue 335 type sequence H description BINDING SITE FOR RESIDUE EDO B 49 source : EC9 152) chain B residue 361 type sequence T description BINDING SITE FOR RESIDUE EDO B 49 source : EC9 153) chain A residue 193 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 154) chain B residue 323 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 155) chain A residue 246 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 156) chain A residue 259 type BINDING sequence Y description source Swiss-Prot : SWS_FT_FI1 157) chain A residue 266 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI1 158) chain A residue 323 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 159) chain B residue 193 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 160) chain B residue 246 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 161) chain B residue 259 type BINDING sequence Y description source Swiss-Prot : SWS_FT_FI1 162) chain B residue 266 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI1 163) chain A residue 249 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|PubMed:21167174 source Swiss-Prot : SWS_FT_FI2 164) chain A residue 251 type BINDING sequence D description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|PubMed:21167174 source Swiss-Prot : SWS_FT_FI2 165) chain A residue 321 type BINDING sequence Y description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|PubMed:21167174 source Swiss-Prot : SWS_FT_FI2 166) chain B residue 249 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|PubMed:21167174 source Swiss-Prot : SWS_FT_FI2 167) chain B residue 251 type BINDING sequence D description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|PubMed:21167174 source Swiss-Prot : SWS_FT_FI2 168) chain B residue 321 type BINDING sequence Y description BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|PubMed:21167174 source Swiss-Prot : SWS_FT_FI2

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