eF-site ID 3pt2-A
PDB Code 3pt2
Chain A

click to enlarge
Title Structure of a viral OTU domain protease bound to Ubiquitin
Classification HYDROLASE/PROTEIN BINDING
Compound RNA polymerase
Source Homo sapiens (Human) (Q5U5U6_HUMAN)
Sequence A:  PGXDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDG
NCFYHSIAELTXPNKTDHSYHYIKRLTESAARKYYQEEPE
ARLVGLSLEDYLKRXLSDNEWGSTLEASXLAKEXGITIII
WTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRIL
PQFE
Description


Functional site

1) chain A
residue 50
type
sequence X
description BINDING SITE FOR RESIDUE SO4 A 185
source : AC1

2) chain A
residue 52
type
sequence N
description BINDING SITE FOR RESIDUE SO4 A 185
source : AC1

3) chain A
residue 54
type
sequence T
description BINDING SITE FOR RESIDUE SO4 A 185
source : AC1

4) chain A
residue 57
type
sequence S
description BINDING SITE FOR RESIDUE SO4 A 185
source : AC1

5) chain A
residue 60
type
sequence Y
description BINDING SITE FOR RESIDUE SO4 A 185
source : AC1

6) chain A
residue 63
type
sequence R
description BINDING SITE FOR RESIDUE SO4 A 185
source : AC1

7) chain A
residue 49
type
sequence T
description BINDING SITE FOR RESIDUE ACT A 186
source : AC2

8) chain A
residue 37
type
sequence D
description BINDING SITE FOR RESIDUE 4LJ B 76
source : AC3

9) chain A
residue 38
type
sequence G
description BINDING SITE FOR RESIDUE 4LJ B 76
source : AC3

10) chain A
residue 40
type
sequence C
description BINDING SITE FOR RESIDUE 4LJ B 76
source : AC3

11) chain A
residue 99
type
sequence W
description BINDING SITE FOR RESIDUE 4LJ B 76
source : AC3

12) chain A
residue 150
type
sequence T
description BINDING SITE FOR RESIDUE 4LJ B 76
source : AC3

13) chain A
residue 151
type
sequence H
description BINDING SITE FOR RESIDUE 4LJ B 76
source : AC3

14) chain A
residue 75
type
sequence E
description BINDING SITE FOR RESIDUE SO4 B 77
source : AC4

15) chain A
residue 81
type
sequence L
description BINDING SITE FOR RESIDUE SO4 B 78
source : AC5

16) chain A
residue 99
type
sequence W
description BINDING SITE FOR RESIDUE SO4 B 78
source : AC5

17) chain A
residue 40
type ACT_SITE
sequence C
description For ubiquitin thioesterase activity => ECO:0000269|PubMed:21228232, ECO:0000269|PubMed:21266548
source Swiss-Prot : SWS_FT_FI1

18) chain A
residue 153
type ACT_SITE
sequence D
description For ubiquitin thioesterase activity => ECO:0000269|PubMed:21228232, ECO:0000269|PubMed:21266548
source Swiss-Prot : SWS_FT_FI1

19) chain A
residue 151
type ACT_SITE
sequence H
description For ubiquitin thioesterase activity => ECO:0000269|PubMed:21228232, ECO:0000269|PubMed:21266548, ECO:0000305|PubMed:18078692
source Swiss-Prot : SWS_FT_FI2


Display surface

Download
Links