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eF-site ID
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3psc-A |
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PDB Code
|
3psc |
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Chain
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A |
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click to enlarge
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Title
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Bovine GRK2 in complex with Gbetagamma subunits |
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Classification
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TRANSFERASE/SIGNALING PROTEIN |
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Compound
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Beta-adrenergic receptor kinase 1 |
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Source
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Bos taurus (Bovine) (GBG2_BOVIN) |
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Sequence
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A: |
SKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLF
RDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREI
FDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQP
YIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTM
NDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIK
MKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLS
FILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHM
HNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPH
ASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGH
SPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGL
LQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPP
PLIPPRGIKLLDSDQELYRNFPLTISERWQQEVAETVFDT
INAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKM
GWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQI
KERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREA
QQLVQRVPKMKNKP
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Description
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Functional site
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|
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1)
|
chain |
A |
| residue |
220 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Cysteine methyl ester => ECO:0000269|PubMed:1903391
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
|
chain |
A |
| residue |
197-220 |
| type |
prosite |
| sequence |
IGRGGFGEVYGCRKADTGKMYAMK
|
| description |
PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGRGGFGEVYgCrkadtgkm..........YAMK
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| source |
prosite : PS00107
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3)
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chain |
A |
| residue |
313-325 |
| type |
prosite |
| sequence |
VVYRDLKPANILL
|
| description |
PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VvYrDLKpaNILL
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| source |
prosite : PS00108
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