eF-site ID 3pag-AB PDB Code 3pag Chain A, B click to enlarge Title Crystal structure of the V130D mutant of OXA-24/40 in complex with doripenem Classification HYDROLASE/ANTIBIOTIC Compound Beta-lactamase Source null (Q8RLA6_ACIBA) Sequence A:  MHISSQQHEKAIKSYFDEAQTQGVIIIKEGKNLSTYGNAL ARANKEYVPASTFKMLNALIGLENHKATTNEIFKWDGKKR TYPMWEKDMTLGEAMALSADPVYQELARRTGLELMQKEVK RVNFGNTNIGTQVDNFWLVGPLKITPVQEVNFADDLAHNR LPFKLETQEEVKKMLLIKEVNGSKIYAKSGWGMGVTPQVG WLTGWVEQANGKKIPFSLNLEMKEGMSGSIRNEITYKSLE NLGII B:  MHISSQQHEKAIKSYFDEAQTQGVIIIKEGKNLSTYGNAL ARANKEYVPASTFKMLNALIGLENHKATTNEIFKWDGKKR TYPMWEKDMTLGEAMALSADPVYQELARRTGLELMQKEVK RVNFGNTNIGTQVDNFWLVGPLKITPVQEVNFADDLAHNR LPFKLETQEEVKKMLLIKEVNGSKIYAKSGWGMGVTPQVG WLTGWVEQANGKKIPFSLNLEMKEGMSGSIRNEITYKSLE NLGII Description Functional site 1) chain A residue 80 type sequence A description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 2) chain A residue 81 type sequence S description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 3) chain A residue 127 type sequence L description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 4) chain A residue 128 type sequence S description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 5) chain A residue 130 type sequence D description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 6) chain A residue 168 type sequence L description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 7) chain A residue 219 type sequence S description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 8) chain A residue 220 type sequence G description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 9) chain A residue 221 type sequence W description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 10) chain A residue 258 type sequence G description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 11) chain A residue 259 type sequence S description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 12) chain A residue 261 type sequence R description BINDING SITE FOR RESIDUE 4J6 A 300 source : AC1 13) chain A residue 142 type sequence L description BINDING SITE FOR RESIDUE SO4 A 1 source : AC2 14) chain A residue 143 type sequence E description BINDING SITE FOR RESIDUE SO4 A 1 source : AC2 15) chain A residue 194 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2 source : AC3 16) chain A residue 195 type sequence L description BINDING SITE FOR RESIDUE SO4 A 2 source : AC3 17) chain A residue 178 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 8 source : AC4 18) chain A residue 181 type sequence N description BINDING SITE FOR RESIDUE SO4 A 8 source : AC4 19) chain B residue 178 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 8 source : AC4 20) chain B residue 80 type sequence A description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 21) chain B residue 81 type sequence S description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 22) chain B residue 128 type sequence S description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 23) chain B residue 130 type sequence D description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 24) chain B residue 168 type sequence L description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 25) chain B residue 219 type sequence S description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 26) chain B residue 220 type sequence G description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 27) chain B residue 221 type sequence W description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 28) chain B residue 258 type sequence G description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 29) chain B residue 259 type sequence S description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 30) chain B residue 261 type sequence R description BINDING SITE FOR RESIDUE 4J6 B 300 source : AC5 31) chain B residue 141 type sequence G description BINDING SITE FOR RESIDUE SO4 B 4 source : AC6 32) chain B residue 142 type sequence L description BINDING SITE FOR RESIDUE SO4 B 4 source : AC6 33) chain B residue 143 type sequence E description BINDING SITE FOR RESIDUE SO4 B 4 source : AC6 34) chain B residue 226 type sequence T description BINDING SITE FOR RESIDUE SO4 B 5 source : AC7 35) chain B residue 227 type sequence P description BINDING SITE FOR RESIDUE SO4 B 5 source : AC7 36) chain B residue 228 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 5 source : AC7 37) chain A residue 178 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 7 source : AC8 38) chain B residue 178 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 7 source : AC8 39) chain B residue 181 type sequence N description BINDING SITE FOR RESIDUE SO4 B 7 source : AC8

Display surface Download Links