eF-site ID 3p57-ABCDEFGHIJKLP PDB Code 3p57 Chain A, B, C, D, E, F, G, H, I, J, K, L, P click to enlarge Title Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA Classification TRANSFERASE/TRANSCRIPTION ACTIVATOR/DNA Compound Myocyte-specific enhancer factor 2A Source (3P57) Sequence A:  GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN SDIVEALNKK B:  GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN SDIVEALNKK C:  GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN SDIVEALNKK D:  GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN SDIVEALNKK E:  AACTATTTATAAGA F:  TTCTTATAAATAGTT G:  AAACTATTTATAAGA H:  TCTTATAAATAGTT I:  GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN SDIVEALNKK J:  GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN SDIVEALNKK K:  AAACTATTTATAAGA L:  TTCTTATAAATAGTT P:  HMSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR VVQHTKGCCPICKQLIALCCYHAKHCQENKCPVPFCLNIK QKLRQQQLQHRLQQAQMLRRRMASM Description Functional site 1) chain P residue 22 type sequence H description BINDING SITE FOR RESIDUE ZN P 120 source : AC1 2) chain P residue 26 type sequence C description BINDING SITE FOR RESIDUE ZN P 120 source : AC1 3) chain P residue 31 type sequence C description BINDING SITE FOR RESIDUE ZN P 120 source : AC1 4) chain P residue 36 type sequence C description BINDING SITE FOR RESIDUE ZN P 120 source : AC1 5) chain P residue 45 type sequence H description BINDING SITE FOR RESIDUE ZN P 121 source : AC2 6) chain P residue 49 type sequence C description BINDING SITE FOR RESIDUE ZN P 121 source : AC2 7) chain P residue 57 type sequence C description BINDING SITE FOR RESIDUE ZN P 121 source : AC2 8) chain P residue 60 type sequence C description BINDING SITE FOR RESIDUE ZN P 121 source : AC2 9) chain P residue 70 type sequence H description BINDING SITE FOR RESIDUE ZN P 122 source : AC3 10) chain P residue 74 type sequence C description BINDING SITE FOR RESIDUE ZN P 122 source : AC3 11) chain P residue 79 type sequence C description BINDING SITE FOR RESIDUE ZN P 122 source : AC3 12) chain P residue 81 type sequence V description BINDING SITE FOR RESIDUE ZN P 122 source : AC3 13) chain P residue 84 type sequence C description BINDING SITE FOR RESIDUE ZN P 122 source : AC3 14) chain A residue 3-57 type prosite sequence RKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCE IALIIFNSSNKLFQY description MADS_BOX_1 MADS-box domain signature. RkKiqitrImDernRqvTFtKRKfgLmKKAyELSvLcdceIaLIIfnssnkLfqY source prosite : PS00350 15) chain P residue 6-87 type ZN_FING sequence GDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQH TKGCCPICKQLIALCCYHAKHCQENKCPVPFCLNI description TAZ-type 2 => ECO:0000255|PROSITE-ProRule:PRU00203 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 58-86 type ZN_FING sequence ASTDMDKVLLKYTEYNEPHESRTNSDIVE description TAZ-type 2 => ECO:0000255|PROSITE-ProRule:PRU00203 source Swiss-Prot : SWS_FT_FI1 17) chain C residue 58-86 type ZN_FING sequence ASTDMDKVLLKYTEYNEPHESRTNSDIVE description TAZ-type 2 => ECO:0000255|PROSITE-ProRule:PRU00203 source Swiss-Prot : SWS_FT_FI1 18) chain D residue 58-86 type ZN_FING sequence ASTDMDKVLLKYTEYNEPHESRTNSDIVE description TAZ-type 2 => ECO:0000255|PROSITE-ProRule:PRU00203 source Swiss-Prot : SWS_FT_FI1 19) chain I residue 58-86 type ZN_FING sequence ASTDMDKVLLKYTEYNEPHESRTNSDIVE description TAZ-type 2 => ECO:0000255|PROSITE-ProRule:PRU00203 source Swiss-Prot : SWS_FT_FI1 20) chain J residue 58-86 type ZN_FING sequence ASTDMDKVLLKYTEYNEPHESRTNSDIVE description TAZ-type 2 => ECO:0000255|PROSITE-ProRule:PRU00203 source Swiss-Prot : SWS_FT_FI1 21) chain P residue 4 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 22) chain B residue 59 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 23) chain C residue 59 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 24) chain D residue 59 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 25) chain I residue 59 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 26) chain J residue 59 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2

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