|
|
eF-site ID
|
3p2x-B |
|
PDB Code
|
3p2x |
|
Chain
|
B |
|
click to enlarge
|
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Title
|
Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity |
|
Classification
|
HORMONE |
|
Compound
|
Insulin |
|
Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
|
Sequence
|
B: |
FVNQHLCXSHLVEALYLVCGERGFFYTPKT
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN B 31
|
| source |
: AC1
|
|
|
2)
|
chain |
B |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN B 31
|
| source |
: AC1
|
|
|
3)
|
chain |
B |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN B 31
|
| source |
: AC1
|
|
|
|