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eF-site ID
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3okj-J |
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PDB Code
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3okj |
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Chain
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J |
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click to enlarge
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Title
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Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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Proteasome component Y7 |
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Source
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ORGANISM_COMMON: yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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J: |
MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSP
HTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAV
SSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID
YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL
LKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDFQAQ
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Description
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Functional site
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1)
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chain |
J |
| residue |
4-51 |
| type |
prosite |
| sequence |
LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLM
SFAGEAGD
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| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAVtFkdGVILGADsrtttgayianrvtd.KltrvhdkiwccrsGsaAD
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| source |
prosite : PS00854
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