eF-site ID 3oix-ABCD PDB Code 3oix Chain A, B, C, D click to enlarge Title Crystal structure of the putative dihydroorotate dehydrogenase from Streptococcus mutans Classification OXIDOREDUCTASE Compound Putative dihydroorotate dehydrogenase; dihydroorotate oxidase Source Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (Q8DVA1_STRMU) Sequence A:  VSTHTTIGSFDFDNCLMNAAGVYCMTREELAAIDHSEAGS FVTXTGTLEERAGNPQPRYADTKLGSINSMGLPNLGINYY LDYVTELQKQPDSKNHFLSLVGMSPEETHTILXMVEASKY QGLVELNLSCPNVPGXPQIAYDFETTDQILSEVFTYFTKP LGIKLPPYFDIVHFDQAAAIFNXYPLTFVNCINSIGNGLV IEDETVVIXPKNGFGGIGGDYVKPTALANVHAFYKRLNPS IQIIGTGGVXTGRDAFEHILCGASMVQIGTALHQEGPQIF KRITKELXAIMTEKGYETLEDFRGKLNAMA B:  VSTHTTIGSFDFDNCLMNAAGVYCMTREELAAIDHSEAGS FVTXTGTLEERAGNPQPRYADTKLGSINSMGLPNLGINYY LDYVTELQKQPDSKNHFLSLVGMSPEETHTILXMVEASKY QGLVELNLSCPNVPGXPQIAYDFETTDQILSEVFTYFTKP LGIKLPPYFDIVHFDQAAAIFNXYPLTFVNCINSIGNGLV IEDETVVIXPKNGFGGIGGDYVKPTALANVHAFYKRLNPS IQIIGTGGVXTGRDAFEHILCGASMVQIGTALHQEGPQIF KRITKELXAIMTEKGYETLEDFRGKLNAMA C:  VSTHTTIGSFDFDNCLMNAAGVYCMTREELAAIDHSEAGS FVTXTGTLEERAGNPQPRYADTKLGSINSMGLPNLGINYY LDYVTELQKQPDSKNHFLSLVGMSPEETHTILXMVEASKY QGLVELNLSCPNVPGXPQIAYDFETTDQILSEVFTYFTKP LGIKLPPYFDIVHFDQAAAIFNXYPLTFVNCINSIGNGLV IEDETVVIXPKNGFGGIGGDYVKPTALANVHAFYKRLNPS IQIIGTGGVXTGRDAFEHILCGASMVQIGTALHQEGPQIF KRITKELXAIMTEKGYETLEDFRGKLNAMA D:  VSTHTTIGSFDFDNCLMNAAGVYCMTREELAAIDHSEAGS FVTXTGTLEERAGNPQPRYADTKLGSINSMGLPNLGINYY LDYVTELQKQPDSKNHFLSLVGMSPEETHTILXMVEASKY QGLVELNLSCPNVPGXPQIAYDFETTDQILSEVFTYFTKP LGIKLPPYFDIVHFDQAAAIFNXYPLTFVNCINSIGNGLV IEDETVVIXPKNGFGGIGGDYVKPTALANVHAFYKRLNPS IQIIGTGGVXTGRDAFEHILCGASMVQIGTALHQEGPQIF KRITKELXAIMTEKGYETLEDFRGKLNAM Description Functional site 1) chain A residue 20 type sequence A description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 2) chain A residue 21 type sequence A description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 3) chain A residue 22 type sequence G description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 4) chain A residue 46 type sequence T description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 5) chain A residue 60 type sequence Y description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 6) chain A residue 69 type sequence N description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 7) chain A residue 71 type sequence M description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 8) chain A residue 128 type sequence N description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 9) chain A residue 165 type sequence K description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 10) chain A residue 193 type sequence I description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 11) chain A residue 194 type sequence N description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 12) chain A residue 219 type sequence G description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 13) chain A residue 220 type sequence G description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 14) chain A residue 247 type sequence T description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 15) chain A residue 248 type sequence G description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 16) chain A residue 249 type sequence G description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 17) chain A residue 270 type sequence G description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 18) chain A residue 271 type sequence T description BINDING SITE FOR RESIDUE FMN A 400 source : AC1 19) chain A residue 142 type sequence Y description BINDING SITE FOR RESIDUE GOL A 500 source : AC2 20) chain A residue 144 type sequence F description BINDING SITE FOR RESIDUE GOL A 500 source : AC2 21) chain A residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL A 500 source : AC2 22) chain B residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL A 500 source : AC2 23) chain B residue 20 type sequence A description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 24) chain B residue 21 type sequence A description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 25) chain B residue 22 type sequence G description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 26) chain B residue 46 type sequence T description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 27) chain B residue 60 type sequence Y description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 28) chain B residue 69 type sequence N description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 29) chain B residue 71 type sequence M description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 30) chain B residue 128 type sequence N description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 31) chain B residue 165 type sequence K description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 32) chain B residue 193 type sequence I description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 33) chain B residue 194 type sequence N description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 34) chain B residue 219 type sequence G description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 35) chain B residue 220 type sequence G description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 36) chain B residue 247 type sequence T description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 37) chain B residue 248 type sequence G description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 38) chain B residue 249 type sequence G description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 39) chain B residue 270 type sequence G description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 40) chain B residue 271 type sequence T description BINDING SITE FOR RESIDUE FMN B 400 source : AC3 41) chain A residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL B 500 source : AC4 42) chain B residue 142 type sequence Y description BINDING SITE FOR RESIDUE GOL B 500 source : AC4 43) chain B residue 144 type sequence F description BINDING SITE FOR RESIDUE GOL B 500 source : AC4 44) chain B residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL B 500 source : AC4 45) chain C residue 20 type sequence A description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 46) chain C residue 21 type sequence A description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 47) chain C residue 22 type sequence G description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 48) chain C residue 46 type sequence T description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 49) chain C residue 60 type sequence Y description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 50) chain C residue 69 type sequence N description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 51) chain C residue 71 type sequence M description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 52) chain C residue 128 type sequence N description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 53) chain C residue 165 type sequence K description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 54) chain C residue 193 type sequence I description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 55) chain C residue 194 type sequence N description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 56) chain C residue 219 type sequence G description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 57) chain C residue 220 type sequence G description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 58) chain C residue 247 type sequence T description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 59) chain C residue 248 type sequence G description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 60) chain C residue 249 type sequence G description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 61) chain C residue 270 type sequence G description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 62) chain C residue 271 type sequence T description BINDING SITE FOR RESIDUE FMN C 400 source : AC5 63) chain C residue 142 type sequence Y description BINDING SITE FOR RESIDUE GOL C 500 source : AC6 64) chain C residue 144 type sequence F description BINDING SITE FOR RESIDUE GOL C 500 source : AC6 65) chain C residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL C 500 source : AC6 66) chain D residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL C 500 source : AC6 67) chain D residue 20 type sequence A description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 68) chain D residue 21 type sequence A description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 69) chain D residue 22 type sequence G description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 70) chain D residue 46 type sequence T description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 71) chain D residue 60 type sequence Y description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 72) chain D residue 69 type sequence N description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 73) chain D residue 71 type sequence M description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 74) chain D residue 128 type sequence N description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 75) chain D residue 165 type sequence K description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 76) chain D residue 193 type sequence I description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 77) chain D residue 194 type sequence N description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 78) chain D residue 219 type sequence G description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 79) chain D residue 220 type sequence G description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 80) chain D residue 247 type sequence T description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 81) chain D residue 248 type sequence G description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 82) chain D residue 249 type sequence G description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 83) chain D residue 270 type sequence G description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 84) chain D residue 271 type sequence T description BINDING SITE FOR RESIDUE FMN D 400 source : AC7 85) chain C residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL D 500 source : AC8 86) chain D residue 142 type sequence Y description BINDING SITE FOR RESIDUE GOL D 500 source : AC8 87) chain D residue 144 type sequence F description BINDING SITE FOR RESIDUE GOL D 500 source : AC8 88) chain D residue 174 type sequence H description BINDING SITE FOR RESIDUE GOL D 500 source : AC8 89) chain A residue 244-264 type prosite sequence IIGTGGVXTGRDAFEHILCGA description DHODEHASE_2 Dihydroorotate dehydrogenase signature 2. IIGtGGVkTgrdAfeHIlCGA source prosite : PS00912

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