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eF-site ID
|
3o8o-A |
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PDB Code
|
3o8o |
|
Chain
|
A |
|
click to enlarge
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Title
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Structure of phosphofructokinase from Saccharomyces cerevisiae |
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Classification
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TRANSFERASE |
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Compound
|
6-phosphofructokinase subunit alpha |
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Source
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(K6PF2_YEAST) |
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Sequence
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A: |
KKKIAVMTSGGDSPGMNAAVRAVVRTGIHFGCDVFAVYEG
YEGLLRGGKYLKKMAWEDVRGWLSEGGTLIGTARSMEFRK
REGRRQAAGNLISQGIDALVVCGGDGSLTGADLFRHEWPS
LVDELVAEGRFTKEEVAPYKNLSIVGLVGSIDNDMSGTDS
TIGAYSALERICEMVDYIDATAKSHSRAFVVEVMGRHCGW
LALMAGIATGADYIFIPERAVPHGKWQDELKEVCQRHRSK
GRRNNTIIVAEGALDDQLNPVTANDVKDALIELGLDTKVT
ILGHVQRGGTAVAHDRWLATLQGVDAVKAVLEFTPETPSP
LIGILENKIIRMPLVESVKLTKSVATAIENKDFDKAISLR
DTEFIELYENFLSTTVKDDGSELLPVSDRLNIGIVHVGAP
SAALNAATRAATLYCLSHGHKPYAIMNGFSGLIQTGEVKE
LSWIDVENWHNLGGSEIGTNRSVASEDLGTIAYYFQKNKL
DGLIILGGFEGFRSLKQLRDGRTQHPIFNIPMCLIPATVS
NNVPGTEYSLGVDTCLNALVNYTDDIKQSASATRRRVFVC
EVQGGHSGYIASFTGLITGAVSVYTPEKKIDLASIREDIT
LLKENFRHDKGENRNGKLLVRNEQASSVYSTQLLADIISE
ASKGKFGVRTAIPGHVQQGGVPSSKDRVTASRFAVKCIKF
IEQWNKKNEEDDSAAVICVNGSHVSFKPIANLWENETNVE
LRKGFEVHWAEYNKIGDILSGRLKLRAEVA
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
450 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0007744|PubMed:19779198
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
2)
|
chain |
A |
| residue |
625 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
3)
|
chain |
A |
| residue |
217 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:19779198
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
4)
|
chain |
A |
| residue |
482-500 |
| type |
prosite |
| sequence |
KVTILGHVQRGGTAVAHDR
|
| description |
PHOSPHOFRUCTOKINASE Phosphofructokinase signature. RittlGHvQRGGtavayDR
|
| source |
prosite : PS00433
|
|
|
5)
|
chain |
A |
| residue |
853-871 |
| type |
prosite |
| sequence |
RTAIPGHVQQGGVPSSKDR
|
| description |
PHOSPHOFRUCTOKINASE Phosphofructokinase signature. RittlGHvQRGGtavayDR
|
| source |
prosite : PS00433
|
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