eF-site ID 3o2y-A PDB Code 3o2y Chain A click to enlarge Title Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid Classification ISOMERASE Compound Prostaglandin-H2 D-isomerase Source Homo sapiens (Human) (PTGDS_HUMAN) Sequence A:  SVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMAKSV VAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYR SPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATL YSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMT Description (1)  Prostaglandin-H2 D-isomerase (E.C.5.3.99.2) Functional site 1) chain A residue 45 type sequence S description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 2) chain A residue 48 type sequence L description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 3) chain A residue 55 type sequence L description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 4) chain A residue 59 type sequence K description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 5) chain A residue 62 type sequence L description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 6) chain A residue 64 type sequence M description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 7) chain A residue 81 type sequence S description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 8) chain A residue 83 type sequence F description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 9) chain A residue 94 type sequence M description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 10) chain A residue 145 type sequence M description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 11) chain A residue 147 type sequence T description BINDING SITE FOR RESIDUE OLA A 200 source : AC1 12) chain A residue 52 type sequence S description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 13) chain A residue 79 type sequence L description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 14) chain A residue 94 type sequence M description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 15) chain A residue 116 type sequence Y description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 16) chain A residue 133 type sequence S description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 17) chain A residue 143 type sequence F description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 18) chain A residue 145 type sequence M description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 19) chain A residue 149 type sequence Y description BINDING SITE FOR RESIDUE PLM A 201 source : AC2 20) chain A residue 142 type sequence D description BINDING SITE FOR RESIDUE PLM B 203 source : AC4 21) chain A residue 65 type ACT_SITE sequence A description Nucleophile => ECO:0000269|PubMed:20667974 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 29 type CARBOHYD sequence S description O-linked (GalNAc...) serine => ECO:0000269|PubMed:23234360 source Swiss-Prot : SWS_FT_FI2 23) chain A residue 78 type CARBOHYD sequence N description N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:8336134 source Swiss-Prot : SWS_FT_FI4 24) chain A residue 51 type CARBOHYD sequence N description N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:8336134 source Swiss-Prot : SWS_FT_FI3 25) chain A residue 33-46 type prosite sequence NFQQDKFLGRWFSA description LIPOCALIN Lipocalin signature. NFQqdKFLGRWFSA source prosite : PS00213

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