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Functional site
| 1) | chain | A |
| residue | 189 | |
| type | ||
| sequence | R | |
| description | BINDING SITE FOR RESIDUE SO4 A 801 | |
| source | : AC1 | |
| 2) | chain | A |
| residue | 192 | |
| type | ||
| sequence | R | |
| description | BINDING SITE FOR RESIDUE SO4 A 801 | |
| source | : AC1 | |
| 3) | chain | A |
| residue | 230 | |
| type | ||
| sequence | Y | |
| description | BINDING SITE FOR RESIDUE SO4 A 801 | |
| source | : AC1 | |
| 4) | chain | A |
| residue | 69 | |
| type | ||
| sequence | R | |
| description | BINDING SITE FOR RESIDUE SO4 A 802 | |
| source | : AC2 | |
| 5) | chain | A |
| residue | 72 | |
| type | ||
| sequence | R | |
| description | BINDING SITE FOR RESIDUE SO4 A 802 | |
| source | : AC2 | |
| 6) | chain | A |
| residue | 150 | |
| type | ||
| sequence | R | |
| description | BINDING SITE FOR RESIDUE SO4 A 802 | |
| source | : AC2 | |
| 7) | chain | A |
| residue | 255 | |
| type | ||
| sequence | T | |
| description | BINDING SITE FOR RESIDUE SO4 B 901 | |
| source | : AC3 | |
| 8) | chain | A |
| residue | 147-159 | |
| type | prosite | |
| sequence | IIHRDLKPSNIVV | |
| description | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpsNIVV | |
| source | prosite : PS00108 | |
| 9) | chain | A |
| residue | 61-163 | |
| type | prosite | |
| sequence |
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEE FQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIK HLHSAGIIHRDLKPSNIVVKSDC |
|
| description | MAPK MAP kinase signature. FqnqthakrayRElvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqmeldhermsyllyqmlcgikhlhsagiih..........RDlKpsnivvksdC | |
| source | prosite : PS01351 | |
| 10) | chain | A |
| residue | 151 | |
| type | ACT_SITE | |
| sequence | D | |
| description | Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027 | |
| source | Swiss-Prot : SWS_FT_FI1 | |
| 11) | chain | A |
| residue | 55 | |
| type | BINDING | |
| sequence | K | |
| description | BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 | |
| source | Swiss-Prot : SWS_FT_FI2 | |
| 12) | chain | A |
| residue | 32 | |
| type | BINDING | |
| sequence | I | |
| description | BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 | |
| source | Swiss-Prot : SWS_FT_FI2 | |
| 13) | chain | A |
| residue | 116 | |
| type | MOD_RES | |
| sequence | C | |
| description | S-nitrosocysteine => ECO:0000250|UniProtKB:P49185 | |
| source | Swiss-Prot : SWS_FT_FI3 | |
| 14) | chain | A |
| residue | 183 | |
| type | MOD_RES | |
| sequence | E | |
| description | Phosphothreonine; by MAP2K7 => ECO:0000269|PubMed:11062067 | |
| source | Swiss-Prot : SWS_FT_FI4 | |
| 15) | chain | A |
| residue | 185 | |
| type | MOD_RES | |
| sequence | E | |
| description | Phosphotyrosine; by MAP2K4 => ECO:0000269|PubMed:11062067 | |
| source | Swiss-Prot : SWS_FT_FI5 | |