eF-site ID 3nzj-Y PDB Code 3nzj Chain Y click to enlarge Title Crystal structure of yeast 20S proteasome in complex with ligand 2a Classification hydrolase/hydrolase inhibitor Compound Proteasome component Y7 Source ORGANISM_COMMON: brewer's yeast,lager beer yeast,yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence Y:  TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF LLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAAS KILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRS ILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV KEEEGSFNNVIG Description Functional site 1) chain Y residue 1 type sequence T description BINDING SITE FOR RESIDUE MES Y 212 source : AC2 2) chain Y residue 47 type sequence G description BINDING SITE FOR RESIDUE MES Y 212 source : AC2 3) chain Y residue 129 type sequence S description BINDING SITE FOR RESIDUE MES Y 212 source : AC2 4) chain Y residue 1 type sequence T description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 5) chain Y residue 20 type sequence A description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 6) chain Y residue 21 type sequence T description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 7) chain Y residue 22 type sequence A description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 8) chain Y residue 23 type sequence G description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 9) chain Y residue 31 type sequence V description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 10) chain Y residue 33 type sequence K description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 11) chain Y residue 45 type sequence M description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 12) chain Y residue 47 type sequence G description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 13) chain Y residue 48 type sequence G description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4 14) chain Y residue 49 type sequence A description BINDING SITE FOR CHAIN 4 OF TMC-95A MIMIC LIGAND 2A source : AC4

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