eF-site ID 3nsq-AB PDB Code 3nsq Chain A, B click to enlarge Title Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron Classification TRANSCRIPTION Compound Retinoid X receptor, alpha Source (Q2NL52_HUMAN) Sequence A:  DPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLR AGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGV GAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKG LSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRL PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML B:  PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRA GWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVG AIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGL SNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLP ALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT Description Functional site 1) chain B residue 313 type sequence F description BINDING SITE FOR RESIDUE CHZ B 1 source : AC1 2) chain B residue 346 type sequence F description BINDING SITE FOR RESIDUE CHZ B 1 source : AC1 3) chain B residue 432 type sequence C description BINDING SITE FOR RESIDUE CHZ B 1 source : AC1 4) chain B residue 316 type BINDING sequence R description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1 5) chain B residue 327 type BINDING sequence A description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1 6) chain A residue 316 type BINDING sequence R description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 327 type BINDING sequence A description BINDING => ECO:0000269|PubMed:16107141, ECO:0000269|PubMed:18800767, ECO:0000269|PubMed:19167885, ECO:0007744|PDB:2ACL, ECO:0007744|PDB:3FAL, ECO:0007744|PDB:3FC6 source Swiss-Prot : SWS_FT_FI1

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