eF-site ID 3nex-B PDB Code 3nex Chain B click to enlarge Title V30M mutant human transthyretin (TTR) complexed with GC-24 (V30M:GC-24) Classification TRANSPORT PROTEIN Compound Transthyretin Source Homo sapiens (Human) (TTHY_HUMAN) Sequence B:  CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKT SESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHE HAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP Description Functional site 1) chain B residue 44 type sequence F description BINDING SITE FOR RESIDUE GOL B 1 source : AC3 2) chain B residue 63 type sequence E description BINDING SITE FOR RESIDUE GOL B 1 source : AC3 3) chain B residue 66 type sequence E description BINDING SITE FOR RESIDUE GOL B 1 source : AC3 4) chain B residue 99 type sequence D description BINDING SITE FOR RESIDUE GOL B 1 source : AC3 5) chain B residue 100 type sequence S description BINDING SITE FOR RESIDUE GOL B 1 source : AC3 6) chain B residue 13 type sequence M description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 7) chain B residue 15 type sequence K description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 8) chain B residue 17 type sequence L description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 9) chain B residue 17 type sequence L description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 10) chain B residue 54 type sequence E description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 11) chain B residue 108 type sequence A description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 12) chain B residue 108 type sequence A description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 13) chain B residue 109 type sequence A description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 14) chain B residue 110 type sequence L description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 15) chain B residue 110 type sequence L description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 16) chain B residue 117 type sequence S description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 17) chain B residue 119 type sequence T description BINDING SITE FOR RESIDUE G24 B 126 source : AC4 18) chain B residue 98 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329 source Swiss-Prot : SWS_FT_FI5 19) chain B residue 15 type BINDING sequence K description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 20) chain B residue 54 type BINDING sequence E description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 21) chain B residue 117 type BINDING sequence S description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 22) chain B residue 42 type MOD_RES sequence E description 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 source Swiss-Prot : SWS_FT_FI3 23) chain B residue 10 type MOD_RES sequence C description Sulfocysteine => ECO:0000269|PubMed:17175208, ECO:0007744|PDB:2H4E source Swiss-Prot : SWS_FT_FI2 24) chain B residue 52 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P02767 source Swiss-Prot : SWS_FT_FI4

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