eF-site ID 3nd7-ABCDEF PDB Code 3nd7 Chain A, B, C, D, E, F click to enlarge Title Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine Classification TRANSFERASE Compound Phosphopantetheine adenylyltransferase Source Enterococcus faecalis (Streptococcus faecalis) (COAD_ENTFA) Sequence A:  MRKIALFPGSFDPMTNGHLNLIERSAKLFDEVIIGVFILF TPEEKKYLIEEATKEMPNVRVIMQETQLTVESAKSLGANF LIRGIRNVKDYEYEKDIAKMNQHLAPEIETVFLLAEEPYA HVSSSLLKEVLRFGGDVSDYLPPNIYHALKQK B:  MRKIALFPGSFDPMTNGHLNLIERSAKLFDEVIIGVFILF TPEEKKYLIEEATKEMPNVRVIMQETQLTVESAKSLGANF LIRGIRNVKDYEYEKDIAKMNQHLAPEIETVFLLAEEPYA HVSSSLLKEVLRFGGDVSDYLPPNIYHALKQK C:  MRKIALFPGSFDPMTNGHLNLIERSAKLFDEVIIGVFILF TPEEKKYLIEEATKEMPNVRVIMQETQLTVESAKSLGANF LIRGIRNVKDYEYEKDIAKMNQHLAPEIETVFLLAEEPYA HVSSSLLKEVLRFGGDVSDYLPPNIYHALKQK D:  MRKIALFPGSFDPMTNGHLNLIERSAKLFDEVIIGVFILF TPEEKKYLIEEATKEMPNVRVIMQETQLTVESAKSLGANF LIRGIRNVKDYEYEKDIAKMNQHLAPEIETVFLLAEEPYA HVSSSLLKEVLRFGGDVSDYLPPNIYHALKQK E:  MRKIALFPGSFDPMTNGHLNLIERSAKLFDEVIIGVFILF TPEEKKYLIEEATKEMPNVRVIMQETQLTVESAKSLGANF LIRGIRNVKDYEYEKDIAKMNQHLAPEIETVFLLAEEPYA HVSSSLLKEVLRFGGDVSDYLPPNIYHALKQK F:  MRKIALFPGSFDPMTNGHLNLIERSAKLFDEVIIGVFILF TPEEKKYLIEEATKEMPNVRVIMQETQLTVESAKSLGANF LIRGIRNVKDYEYEKDIAKMNQHLAPEIETVFLLAEEPYA HVSSSLLKEVLRFGGDVSDYLPPNIYHALKQK Description Functional site 1) chain A residue 9 type sequence G description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 2) chain A residue 10 type sequence S description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 3) chain A residue 73 type sequence Q description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 4) chain A residue 74 type sequence L description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 5) chain A residue 75 type sequence T description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 6) chain A residue 99 type sequence Y description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 7) chain A residue 106 type sequence M description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 8) chain A residue 107 type sequence N description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 9) chain C residue 135 type sequence E description BINDING SITE FOR RESIDUE PNY A 501 source : AC1 10) chain B residue 37 type sequence F description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 11) chain B residue 73 type sequence Q description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 12) chain B residue 74 type sequence L description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 13) chain B residue 75 type sequence T description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 14) chain B residue 99 type sequence Y description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 15) chain B residue 103 type sequence I description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 16) chain B residue 106 type sequence M description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 17) chain B residue 107 type sequence N description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 18) chain F residue 135 type sequence E description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 19) chain F residue 139 type sequence F description BINDING SITE FOR RESIDUE PNY B 502 source : AC2 20) chain C residue 73 type sequence Q description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 21) chain C residue 74 type sequence L description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 22) chain C residue 75 type sequence T description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 23) chain C residue 89 type sequence R description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 24) chain C residue 99 type sequence Y description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 25) chain C residue 103 type sequence I description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 26) chain C residue 106 type sequence M description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 27) chain C residue 107 type sequence N description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 28) chain E residue 135 type sequence E description BINDING SITE FOR RESIDUE PNY C 503 source : AC3 29) chain B residue 132 type sequence L description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 30) chain B residue 135 type sequence E description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 31) chain D residue 8 type sequence P description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 32) chain D residue 73 type sequence Q description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 33) chain D residue 74 type sequence L description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 34) chain D residue 75 type sequence T description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 35) chain D residue 99 type sequence Y description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 36) chain D residue 103 type sequence I description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 37) chain D residue 106 type sequence M description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 38) chain D residue 107 type sequence N description BINDING SITE FOR RESIDUE PNY D 504 source : AC4 39) chain A residue 135 type sequence E description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 40) chain E residue 9 type sequence G description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 41) chain E residue 73 type sequence Q description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 42) chain E residue 74 type sequence L description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 43) chain E residue 75 type sequence T description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 44) chain E residue 89 type sequence R description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 45) chain E residue 99 type sequence Y description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 46) chain E residue 106 type sequence M description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 47) chain E residue 107 type sequence N description BINDING SITE FOR RESIDUE PNY E 505 source : AC5 48) chain D residue 135 type sequence E description BINDING SITE FOR RESIDUE PNY F 506 source : AC6 49) chain F residue 74 type sequence L description BINDING SITE FOR RESIDUE PNY F 506 source : AC6 50) chain F residue 75 type sequence T description BINDING SITE FOR RESIDUE PNY F 506 source : AC6 51) chain F residue 99 type sequence Y description BINDING SITE FOR RESIDUE PNY F 506 source : AC6 52) chain F residue 106 type sequence M description BINDING SITE FOR RESIDUE PNY F 506 source : AC6 53) chain F residue 107 type sequence N description BINDING SITE FOR RESIDUE PNY F 506 source : AC6 54) chain A residue 10 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 55) chain D residue 10 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 56) chain D residue 89 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 57) chain E residue 10 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 58) chain E residue 89 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 59) chain F residue 10 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 60) chain F residue 89 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 61) chain A residue 89 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 62) chain B residue 10 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 63) chain B residue 89 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 64) chain C residue 10 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 65) chain C residue 89 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI1 66) chain A residue 18 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 67) chain C residue 90 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 68) chain C residue 100 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 69) chain C residue 125 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 70) chain D residue 18 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 71) chain D residue 90 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 72) chain D residue 100 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 73) chain D residue 125 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 74) chain E residue 18 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 75) chain E residue 90 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 76) chain E residue 100 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 77) chain A residue 90 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 78) chain E residue 125 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 79) chain F residue 18 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 80) chain F residue 90 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 81) chain F residue 100 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 82) chain F residue 125 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 83) chain A residue 100 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 84) chain A residue 125 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 85) chain B residue 18 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 86) chain B residue 90 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 87) chain B residue 100 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 88) chain B residue 125 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 89) chain C residue 18 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000269|PubMed:21912874, ECO:0007744|PDB:3ND6 source Swiss-Prot : SWS_FT_FI2 90) chain A residue 75 type BINDING sequence T description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000305|PubMed:21912874, ECO:0007744|PDB:3ND7 source Swiss-Prot : SWS_FT_FI3 91) chain B residue 75 type BINDING sequence T description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000305|PubMed:21912874, ECO:0007744|PDB:3ND7 source Swiss-Prot : SWS_FT_FI3 92) chain C residue 75 type BINDING sequence T description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000305|PubMed:21912874, ECO:0007744|PDB:3ND7 source Swiss-Prot : SWS_FT_FI3 93) chain D residue 75 type BINDING sequence T description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000305|PubMed:21912874, ECO:0007744|PDB:3ND7 source Swiss-Prot : SWS_FT_FI3 94) chain E residue 75 type BINDING sequence T description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000305|PubMed:21912874, ECO:0007744|PDB:3ND7 source Swiss-Prot : SWS_FT_FI3 95) chain F residue 75 type BINDING sequence T description BINDING => ECO:0000255|HAMAP-Rule:MF_00151, ECO:0000305|PubMed:21912874, ECO:0007744|PDB:3ND7 source Swiss-Prot : SWS_FT_FI3 96) chain A residue 18 type SITE sequence H description Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI4 97) chain B residue 18 type SITE sequence H description Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI4 98) chain C residue 18 type SITE sequence H description Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI4 99) chain D residue 18 type SITE sequence H description Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI4 100) chain E residue 18 type SITE sequence H description Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI4 101) chain F residue 18 type SITE sequence H description Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 source Swiss-Prot : SWS_FT_FI4

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