eF-site ID 3mx2-B PDB Code 3mx2 Chain B click to enlarge Title Lassa fever virus Nucleoprotein complexed with dTTP Classification NUCLEAR PROTEIN Compound Nucleoprotein Source Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV) (NCAP_LASSJ) Sequence B:  KSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEV SNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKS ILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMG NLSSQQLDQRRALLNMIGMAGRDGVVRVWDVKNAELLNNQ FGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPN TSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAG ACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISD TPGERNPYENILYKICLSGDGWPYIASRTSITGRAWENTV VDLGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEI ALYQPSSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFA TQPGLTSAVIDALPRNMVITCQGSDDIRKLLESQGRKDIK LIDIALSKTDSRKYENAVWDQYKDLCHMHTGVVVEKKKEE ITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFR Description Functional site 1) chain B residue 399 type sequence E description BINDING SITE FOR RESIDUE ZN B 570 source : AC3 2) chain B residue 506 type sequence C description BINDING SITE FOR RESIDUE ZN B 570 source : AC3 3) chain B residue 509 type sequence H description BINDING SITE FOR RESIDUE ZN B 570 source : AC3 4) chain B residue 529 type sequence C description BINDING SITE FOR RESIDUE ZN B 570 source : AC3 5) chain B residue 54 type sequence M description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 6) chain B residue 59 type sequence R description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 7) chain B residue 117 type sequence E description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 8) chain B residue 120 type sequence L description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 9) chain B residue 164 type sequence W description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 10) chain B residue 176 type sequence F description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 11) chain B residue 177 type sequence G description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 12) chain B residue 178 type sequence T description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 13) chain B residue 238 type sequence S description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 14) chain B residue 239 type sequence L description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 15) chain B residue 240 type sequence N description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 16) chain B residue 241 type sequence I description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 17) chain B residue 253 type sequence K description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 18) chain B residue 305 type sequence N description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 19) chain B residue 309 type sequence K description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 20) chain B residue 323 type sequence R description BINDING SITE FOR RESIDUE TTP B 800 source : AC4 21) chain B residue 389 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 391 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 533 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 399 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902 source Swiss-Prot : SWS_FT_FI2 25) chain B residue 506 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902 source Swiss-Prot : SWS_FT_FI2 26) chain B residue 509 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902 source Swiss-Prot : SWS_FT_FI2 27) chain B residue 529 type BINDING sequence C description BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902 source Swiss-Prot : SWS_FT_FI2 28) chain B residue 466 type SITE sequence D description Important for exonuclease activity => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links