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eF-site ID
|
3mwp-C |
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PDB Code
|
3mwp |
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Chain
|
C |
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click to enlarge
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Title
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Nucleoprotein structure of lassa fever virus |
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Classification
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NUCLEAR PROTEIN |
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Compound
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Nucleoprotein |
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Source
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Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV) (NCAP_LASSJ) |
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Sequence
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C: |
KSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEV
SNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKS
ILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMG
NLSSQQLDQRRALLNMIGMDGVVRVWDVKNAELLNNQFGT
MPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNTSD
LDRLTQSHPILNMIDTSSLNISGYNFSLGAAVKAGACMLD
GNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERN
PYENILYKICLSGDGWPYIASRTSITGRAWENTVVDGLTY
SQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSS
GCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTS
AVIDALPRNMVITCQGSDDIRKLLESQGRKDIKLIDIALS
KTDSRKYENAVWDQYKDLCHMHTGVVVEKKEEITPHCALM
DCIMFDAAVSGGLVLRAVLPRDMVFR
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Description
|
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Functional site
|
|
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1)
|
chain |
C |
| residue |
399 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE ZN C 570
|
| source |
: AC3
|
|
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2)
|
chain |
C |
| residue |
506 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 570
|
| source |
: AC3
|
|
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3)
|
chain |
C |
| residue |
509 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN C 570
|
| source |
: AC3
|
|
|
4)
|
chain |
C |
| residue |
529 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 570
|
| source |
: AC3
|
|
|
5)
|
chain |
C |
| residue |
389 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
C |
| residue |
391 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
C |
| residue |
533 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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8)
|
chain |
C |
| residue |
506 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
9)
|
chain |
C |
| residue |
509 |
| type |
BINDING |
| sequence |
H
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
10)
|
chain |
C |
| residue |
529 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
11)
|
chain |
C |
| residue |
399 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117, ECO:0000269|PubMed:21262835, ECO:0000269|PubMed:22937163, ECO:0000269|PubMed:23615902
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
12)
|
chain |
C |
| residue |
466 |
| type |
SITE |
| sequence |
D
|
| description |
Important for exonuclease activity => ECO:0000255|HAMAP-Rule:MF_04085, ECO:0000269|PubMed:21085117
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|