eF-site ID 3mr3-A PDB Code 3mr3 Chain A click to enlarge Title Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1) Classification TRANSFERASE/DNA Compound DNA polymerase eta Source Homo sapiens (Human) (3MR3) Sequence A:  GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVV QYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLL AQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEA YVDLTSAVQERLQKLQPISADLLPSTYIEGLPQGETVQKE GMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAI ERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVP QLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTES QLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKN FPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVAT QLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIK NCNTSGIQTEWSPPLTMLFLCATKFSAS Description Functional site 1) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 2) chain A residue 14 type sequence M description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 3) chain A residue 15 type sequence D description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 4) chain A residue 16 type sequence C description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 5) chain A residue 17 type sequence F description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 6) chain A residue 18 type sequence F description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 7) chain A residue 48 type sequence I description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 8) chain A residue 49 type sequence A description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 9) chain A residue 52 type sequence Y description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 10) chain A residue 55 type sequence R description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 11) chain A residue 61 type sequence R description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 12) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 13) chain A residue 231 type sequence K description BINDING SITE FOR RESIDUE DZ4 A 433 source : AC1 14) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE MG A 434 source : AC2 15) chain A residue 14 type sequence M description BINDING SITE FOR RESIDUE MG A 434 source : AC2 16) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE MG A 434 source : AC2 17) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE MG A 435 source : AC3 18) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE MG A 435 source : AC3 19) chain A residue 116 type sequence E description BINDING SITE FOR RESIDUE MG A 435 source : AC3 20) chain A residue 24 type sequence R description BINDING SITE FOR RESIDUE GOL A 436 source : AC4 21) chain A residue 244 type sequence P description BINDING SITE FOR RESIDUE GOL A 436 source : AC4 22) chain A residue 247 type sequence F description BINDING SITE FOR RESIDUE GOL A 436 source : AC4 23) chain A residue 248 type sequence S description BINDING SITE FOR RESIDUE GOL A 436 source : AC4 24) chain A residue 276 type sequence G description BINDING SITE FOR RESIDUE GOL A 436 source : AC4 25) chain A residue 277 type sequence E description BINDING SITE FOR RESIDUE GOL A 436 source : AC4 26) chain A residue 26 type sequence N description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 27) chain A residue 27 type sequence P description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 28) chain A residue 28 type sequence H description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 29) chain A residue 271 type sequence G description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 30) chain A residue 272 type sequence I description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 31) chain A residue 273 type sequence E description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 32) chain A residue 274 type sequence Y description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 33) chain A residue 277 type sequence E description BINDING SITE FOR RESIDUE GOL A 437 source : AC5 34) chain A residue 27 type sequence P description BINDING SITE FOR RESIDUE GOL A 438 source : AC6 35) chain A residue 28 type sequence H description BINDING SITE FOR RESIDUE GOL A 438 source : AC6 36) chain A residue 342 type sequence L description BINDING SITE FOR RESIDUE GOL A 439 source : AC7 37) chain A residue 393 type sequence H description BINDING SITE FOR RESIDUE GOL A 439 source : AC7 38) chain A residue 3 type sequence T description BINDING SITE FOR RESIDUE GOL A 440 source : AC8 39) chain A residue 101 type sequence E description BINDING SITE FOR RESIDUE GOL A 440 source : AC8 40) chain A residue 240 type sequence H description BINDING SITE FOR RESIDUE GOL A 440 source : AC8 41) chain A residue 240 type sequence H description BINDING SITE FOR RESIDUE GOL A 441 source : AC9 42) chain A residue 243 type sequence V description BINDING SITE FOR RESIDUE GOL A 441 source : AC9 43) chain A residue 302 type sequence C description BINDING SITE FOR RESIDUE GOL A 441 source : AC9 44) chain A residue 303 type sequence R description BINDING SITE FOR RESIDUE GOL A 441 source : AC9 45) chain A residue 256 type sequence R description BINDING SITE FOR RESIDUE DZ4 A 442 source : BC1 46) chain A residue 257 type sequence S description BINDING SITE FOR RESIDUE DZ4 A 442 source : BC1 47) chain A residue 262 type sequence L description BINDING SITE FOR RESIDUE DZ4 A 442 source : BC1 48) chain A residue 293 type sequence K description BINDING SITE FOR RESIDUE DZ4 A 442 source : BC1 49) chain A residue 294 type sequence N description BINDING SITE FOR RESIDUE DZ4 A 442 source : BC1 50) chain A residue 297 type sequence W description BINDING SITE FOR RESIDUE DZ4 A 442 source : BC1 51) chain A residue 13 type BINDING sequence D description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 52) chain A residue 14 type BINDING sequence M description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 53) chain A residue 115 type BINDING sequence D description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 54) chain A residue 116 type BINDING sequence E description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 55) chain A residue 61 type BINDING sequence R description BINDING => ECO:0000269|PubMed:27284197 source Swiss-Prot : SWS_FT_FI2

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