|
|
eF-site ID
|
3mor-AB |
|
PDB Code
|
3mor |
|
Chain
|
A, B |
|
click to enlarge
|
|
|
Title
|
Crystal structure of Cathepsin B from Trypanosoma Brucei |
|
Classification
|
HYDROLASE |
|
Compound
|
Cathepsin B-like cysteine protease |
|
Source
|
null (Q6R7Z5_9TRYP) |
|
|
Sequence
|
A: |
SILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQS
ACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSD
CGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSK
SKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYAL
QGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQ
YLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIR
RGSSECGIEDGGSAGIPLAP
|
| B: |
SILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQS
ACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSD
CGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSK
SKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYAL
QGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQ
YLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIR
RGSSECGIEDGGSAGIPLAP
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
116-127 |
| type |
prosite |
| sequence |
QSACGSCWAVAA
|
| description |
THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QSaCGSCWAvAA
|
| source |
prosite : PS00139
|
|
|
2)
|
chain |
A |
| residue |
280-290 |
| type |
prosite |
| sequence |
GGHAVRLVGWG
|
| description |
THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. GGHAVRLVGWG
|
| source |
prosite : PS00639
|
|
|
|