eF-site ID 3mnr-P PDB Code 3mnr Chain P click to enlarge Title Crystal Structure of Benzamide SNX-1321 bound to Hsp90 Classification CHAPERONE Compound Heat shock protein HSP 90-alpha Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence P:  EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDA LDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTG IGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG VGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTD TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIG YPITLFVEK Description Functional site 1) chain P residue 51 type sequence N description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 2) chain P residue 55 type sequence A description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 3) chain P residue 58 type sequence K description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 4) chain P residue 61 type sequence Y description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 5) chain P residue 93 type sequence D description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 6) chain P residue 97 type sequence G description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 7) chain P residue 98 type sequence M description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 8) chain P residue 102 type sequence D description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 9) chain P residue 139 type sequence Y description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 10) chain P residue 162 type sequence W description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 11) chain P residue 184 type sequence T description BINDING SITE FOR RESIDUE SD1 P 233 source : AC1 12) chain P residue 51 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 13) chain P residue 93 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 14) chain P residue 138 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 15) chain P residue 112 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 16) chain P residue 58 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI4 17) chain P residue 84 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI4 18) chain P residue 38-47 type prosite sequence YSNKEIFLRE description HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE source prosite : PS00298

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