|
|
eF-site ID
|
3mls-L |
|
PDB Code
|
3mls |
|
Chain
|
L |
|
click to enlarge
|
|
|
Title
|
Crystal structure of anti-HIV-1 V3 mAb 2557 Fab in complex with a HIV-1 gp120 V3 mimotope |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain |
|
Source
|
ORGANISM_SCIENTIFIC: Homo sapiens; |
|
|
Sequence
|
L: |
SYDLTQPPSVSVSPGQTASISCSGDKLDDKYVSWYYQRPG
QSPVLLMYQDFKRPSGIPERLSGSKSGKTATLTISGTQSL
DEGDYYCQAWDASTGVSGGGTKLTVLFGDGTRLTVLGQPK
AAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKA
DSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKS
YSCQVTHEGSTVEKTVAPT
|
|
|
Description
|
(1) |
Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, Rationally designed V3 mimotope
|
|
Functional site
|
|
|
1)
|
chain |
L |
| residue |
195-201 |
| type |
prosite |
| sequence |
YSCQVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
|
|