eF-site ID 3mks-B PDB Code 3mks Chain B click to enlarge Title Crystal Structure of yeast Cdc4/Skp1 in complex with an allosteric inhibitor SCF-I2 Classification LIGASE/CELL CYCLE Compound Suppressor of kinetochore protein 1 Source (CDC4_YEAST) Sequence B:  LKRDLITSLPFEISLKIFNYLQFEDIINSLGVSQNWNKII RKSTSLWKKLLISENFVSPKGFNSLNLKLSQKYPKLSQQD RLRLSFLENIFILKNWYNPKFVPQRTTLRGHMTSVITCLQ FEDNYVITGADDKMIRVYDSINKKFLLQLSGHDGGVWALK YAHGGILVSGSTDRTVRVWDIKKGCCTHVFEGHNSTVRCL DIVEYKNIKYIVTGSRDNTLHVWKLPKDYPLVFHTPEENP YFVGVLRGHMASVRTVSGHGNIVVSGSYDNTLIVWDVAQM KCLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLE NGELMYTLQGHTALVGLLRLSDKFLVSAAADGSIRGWDAN DYSRKFSYHHTNLSAITTFYVSDNILVSGSENQFNIYNLR SGKLVHANILKDADQIWSVNFKGKTLVAAVEKDGQSFLEI LDFS Description Functional site 1) chain B residue 280 type sequence F description BINDING SITE FOR RESIDUE SO4 B 1 source : AC1 2) chain B residue 311 type sequence K description BINDING SITE FOR RESIDUE SO4 B 1 source : AC1 3) chain B residue 312 type sequence S description BINDING SITE FOR RESIDUE SO4 B 1 source : AC1 4) chain B residue 314 type sequence S description BINDING SITE FOR RESIDUE SO4 B 1 source : AC1 5) chain B residue 280 type sequence F description BINDING SITE FOR RESIDUE SO4 B 3 source : AC2 6) chain B residue 389 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 4 source : AC3 7) chain B residue 639 type sequence R description BINDING SITE FOR RESIDUE SO4 B 4 source : AC3 8) chain B residue 720 type sequence N description BINDING SITE FOR RESIDUE SO4 B 4 source : AC3 9) chain B residue 706 type sequence H description BINDING SITE FOR RESIDUE SO4 B 6 source : AC4 10) chain B residue 707 type sequence A description BINDING SITE FOR RESIDUE SO4 B 6 source : AC4 11) chain B residue 708 type sequence N description BINDING SITE FOR RESIDUE SO4 B 6 source : AC4 12) chain B residue 709 type sequence I description BINDING SITE FOR RESIDUE SO4 B 6 source : AC4 13) chain B residue 365 type sequence W description BINDING SITE FOR RESIDUE SO4 B 7 source : AC5 14) chain B residue 682 type sequence S description BINDING SITE FOR RESIDUE SO4 B 7 source : AC5 15) chain B residue 685 type sequence I description BINDING SITE FOR RESIDUE SO4 B 7 source : AC5 16) chain B residue 721 type sequence F description BINDING SITE FOR RESIDUE SO4 B 7 source : AC5 17) chain B residue 723 type sequence G description BINDING SITE FOR RESIDUE SO4 B 7 source : AC5 18) chain B residue 436-450 type prosite sequence LVSGSTDRTVRVWDI description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSGstDrTVRVWDI source prosite : PS00678 19) chain B residue 543-557 type prosite sequence VVSGSYDNTLIVWDV description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSGstDrTVRVWDI source prosite : PS00678 20) chain B residue 585-599 type prosite sequence CISASMDTTIRIWDL description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSGstDrTVRVWDI source prosite : PS00678 21) chain B residue 645-659 type prosite sequence LVSAAADGSIRGWDA description WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSGstDrTVRVWDI source prosite : PS00678

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