|
|
eF-site ID
|
3mg0-P |
|
PDB Code
|
3mg0 |
|
Chain
|
P |
|
click to enlarge
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Title
|
Structure of yeast 20S proteasome with bortezomib |
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Classification
|
HYDROLASE |
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Compound
|
Proteasome component Y7 |
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Source
|
ORGANISM_COMMON: brewer's yeast,lager beer yeast,yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
|
Sequence
|
P: |
GSRRYDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMAS
DGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLT
ADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQG
YTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWK
AISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTT
DSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVK
TGIT
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
P |
| residue |
101 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
P |
| residue |
199 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
P |
| residue |
225 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|