|
|
1)
|
chain |
A |
residue |
75 |
type |
|
sequence |
G
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
2)
|
chain |
A |
residue |
76 |
type |
|
sequence |
A
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
3)
|
chain |
A |
residue |
77 |
type |
|
sequence |
G
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
4)
|
chain |
A |
residue |
80 |
type |
|
sequence |
G
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
5)
|
chain |
A |
residue |
95 |
type |
|
sequence |
A
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
6)
|
chain |
A |
residue |
97 |
type |
|
sequence |
K
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
7)
|
chain |
A |
residue |
143 |
type |
|
sequence |
M
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
8)
|
chain |
A |
residue |
144 |
type |
|
sequence |
E
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
9)
|
chain |
A |
residue |
146 |
type |
|
sequence |
M
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
10)
|
chain |
A |
residue |
150 |
type |
|
sequence |
S
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
11)
|
chain |
A |
residue |
153 |
type |
|
sequence |
Q
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
12)
|
chain |
A |
residue |
192 |
type |
|
sequence |
K
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
13)
|
chain |
A |
residue |
194 |
type |
|
sequence |
S
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
14)
|
chain |
A |
residue |
195 |
type |
|
sequence |
N
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
15)
|
chain |
A |
residue |
197 |
type |
|
sequence |
L
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
16)
|
chain |
A |
residue |
208 |
type |
|
sequence |
D
|
description |
BINDING SITE FOR RESIDUE ADP A 535
|
source |
: AC1
|
|
17)
|
chain |
A |
residue |
97 |
type |
|
sequence |
K
|
description |
BINDING SITE FOR RESIDUE MG A 536
|
source |
: AC2
|
|
18)
|
chain |
A |
residue |
195 |
type |
|
sequence |
N
|
description |
BINDING SITE FOR RESIDUE MG A 536
|
source |
: AC2
|
|
19)
|
chain |
A |
residue |
208 |
type |
|
sequence |
D
|
description |
BINDING SITE FOR RESIDUE MG A 536
|
source |
: AC2
|
|
20)
|
chain |
A |
residue |
78 |
type |
|
sequence |
N
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
21)
|
chain |
A |
residue |
97 |
type |
|
sequence |
K
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
22)
|
chain |
A |
residue |
115 |
type |
|
sequence |
L
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
23)
|
chain |
A |
residue |
127 |
type |
|
sequence |
V
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
24)
|
chain |
A |
residue |
141 |
type |
|
sequence |
I
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
25)
|
chain |
A |
residue |
143 |
type |
|
sequence |
M
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
26)
|
chain |
A |
residue |
207 |
type |
|
sequence |
C
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
27)
|
chain |
A |
residue |
208 |
type |
|
sequence |
D
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
28)
|
chain |
A |
residue |
209 |
type |
|
sequence |
F
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
29)
|
chain |
A |
residue |
210 |
type |
|
sequence |
G
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
30)
|
chain |
A |
residue |
211 |
type |
|
sequence |
V
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
31)
|
chain |
A |
residue |
212 |
type |
|
sequence |
S
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
32)
|
chain |
A |
residue |
215 |
type |
|
sequence |
L
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
33)
|
chain |
A |
residue |
216 |
type |
|
sequence |
I
|
description |
BINDING SITE FOR RESIDUE LSG A 7
|
source |
: AC3
|
|
34)
|
chain |
A |
residue |
74-97 |
type |
prosite |
sequence |
LGAGNGGVVFKVSHKPSGLVMARK
|
description |
PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGAGNGGVVFkVshkpsglv..........MARK
|
source |
prosite : PS00107
|
|
35)
|
chain |
A |
residue |
186-198 |
type |
prosite |
sequence |
IMHRDVKPSNILV
|
description |
PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKpsNILV
|
source |
prosite : PS00108
|
|
36)
|
chain |
A |
residue |
190 |
type |
ACT_SITE |
sequence |
D
|
description |
Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
37)
|
chain |
A |
residue |
74 |
type |
BINDING |
sequence |
L
|
description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000269|PubMed:15543157, ECO:0000269|PubMed:17880056, ECO:0000269|PubMed:18951019, ECO:0000269|PubMed:19019675, ECO:0000269|PubMed:19706763, ECO:0000269|PubMed:21310613
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
38)
|
chain |
A |
residue |
143 |
type |
BINDING |
sequence |
M
|
description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000269|PubMed:15543157, ECO:0000269|PubMed:17880056, ECO:0000269|PubMed:18951019, ECO:0000269|PubMed:19019675, ECO:0000269|PubMed:19706763, ECO:0000269|PubMed:21310613
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
39)
|
chain |
A |
residue |
150 |
type |
BINDING |
sequence |
S
|
description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000269|PubMed:15543157, ECO:0000269|PubMed:17880056, ECO:0000269|PubMed:18951019, ECO:0000269|PubMed:19019675, ECO:0000269|PubMed:19706763, ECO:0000269|PubMed:21310613
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
40)
|
chain |
A |
residue |
192 |
type |
BINDING |
sequence |
K
|
description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000269|PubMed:15543157, ECO:0000269|PubMed:17880056, ECO:0000269|PubMed:18951019, ECO:0000269|PubMed:19019675, ECO:0000269|PubMed:19706763, ECO:0000269|PubMed:21310613
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
41)
|
chain |
A |
residue |
208 |
type |
BINDING |
sequence |
D
|
description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000269|PubMed:15543157, ECO:0000269|PubMed:17880056, ECO:0000269|PubMed:18951019, ECO:0000269|PubMed:19019675, ECO:0000269|PubMed:19706763, ECO:0000269|PubMed:21310613
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
42)
|
chain |
A |
residue |
97 |
type |
BINDING |
sequence |
K
|
description |
BINDING => ECO:0000269|PubMed:19161339, ECO:0007744|PDB:3EQH
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
43)
|
chain |
A |
residue |
144 |
type |
BINDING |
sequence |
E
|
description |
BINDING => ECO:0000269|PubMed:19161339, ECO:0007744|PDB:3EQF
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
44)
|
chain |
A |
residue |
194 |
type |
BINDING |
sequence |
S
|
description |
BINDING => ECO:0000269|PubMed:19161339, ECO:0007744|PDB:3EQF
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
45)
|
chain |
A |
residue |
218 |
type |
MOD_RES |
sequence |
S
|
description |
Phosphoserine; by BRAF and RAF1 => ECO:0000269|PubMed:10409742, ECO:0000269|PubMed:20956560, ECO:0000269|PubMed:29433126, ECO:0000269|PubMed:8131746
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
46)
|
chain |
A |
residue |
222 |
type |
MOD_RES |
sequence |
S
|
description |
Phosphoserine; by BRAF and RAF1 => ECO:0000269|PubMed:20956560, ECO:0000269|PubMed:29433126, ECO:0000269|PubMed:8131746
|
source |
Swiss-Prot : SWS_FT_FI6
|
|