eF-site ID 3lu7-B
PDB Code 3lu7
Chain B

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Title Human serum albumin in complex with compound 2
Classification TRANSPORT PROTEIN
Compound Serum albumin
Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens;
Sequence B:  KSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLV
NEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRET
YGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVM
CTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKA
AFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASL
QKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHT
ECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPL
LEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAK
DVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAA
ADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKF
QNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEA
KRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVN
RRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQI
KKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADD
KETCFAEEGKKLVAASQAA
Description (1)  Serum albumin


Functional site
1) chain B
residue 150
type
sequence Y
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
2) chain B
residue 199
type
sequence K
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
3) chain B
residue 202
type
sequence S
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
4) chain B
residue 211
type
sequence F
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
5) chain B
residue 214
type
sequence W
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
6) chain B
residue 218
type
sequence R
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
7) chain B
residue 219
type
sequence L
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
8) chain B
residue 222
type
sequence R
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
9) chain B
residue 242
type
sequence H
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
10) chain B
residue 257
type
sequence R
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
11) chain B
residue 287
type
sequence S
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
12) chain B
residue 290
type
sequence I
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
13) chain B
residue 291
type
sequence A
description BINDING SITE FOR RESIDUE IPX B 586
source : AC2
14) chain B
residue 195
type
sequence K
description BINDING SITE FOR RESIDUE PO4 B 587
source : AC4
15) chain B
residue 199
type
sequence K
description BINDING SITE FOR RESIDUE PO4 B 587
source : AC4
16) chain B
residue 218
type
sequence R
description BINDING SITE FOR RESIDUE PO4 B 587
source : AC4
17) chain B
residue 9
type
sequence H
description BINDING SITE FOR RESIDUE PO4 B 588
source : AC5
18) chain B
residue 12
type
sequence K
description BINDING SITE FOR RESIDUE PO4 B 588
source : AC5
19) chain B
residue 57
type
sequence E
description BINDING SITE FOR RESIDUE PO4 B 588
source : AC5
20) chain B
residue 359
type
sequence K
description BINDING SITE FOR RESIDUE PO4 B 588
source : AC5
21) chain B
residue 419
type MOD_RES
sequence S
description Phosphoserine => ECO:0007744|PubMed:19690332
source Swiss-Prot : SWS_FT_FI13
22) chain B
residue 420
type MOD_RES
sequence T
description Phosphothreonine => ECO:0007744|PubMed:19690332
source Swiss-Prot : SWS_FT_FI14
23) chain B
residue 422
type MOD_RES
sequence T
description Phosphothreonine => ECO:0007744|PubMed:19690332
source Swiss-Prot : SWS_FT_FI14
24) chain B
residue 489
type MOD_RES
sequence S
description Phosphoserine => ECO:0007744|PubMed:24275569
source Swiss-Prot : SWS_FT_FI15
25) chain B
residue 534
type MOD_RES
sequence K
description N6-methyllysine; alternate => ECO:0007744|PubMed:24129315
source Swiss-Prot : SWS_FT_FI16
26) chain B
residue 12
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:3759977
source Swiss-Prot : SWS_FT_FI17
27) chain B
residue 281
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:3759977
source Swiss-Prot : SWS_FT_FI17
28) chain B
residue 317
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:3759977
source Swiss-Prot : SWS_FT_FI17
29) chain B
residue 439
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:3759977
source Swiss-Prot : SWS_FT_FI17
30) chain B
residue 51
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
31) chain B
residue 137
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
32) chain B
residue 162
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
33) chain B
residue 225
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
34) chain B
residue 276
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
35) chain B
residue 313
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
36) chain B
residue 323
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
37) chain B
residue 378
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
38) chain B
residue 413
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
39) chain B
residue 444
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
40) chain B
residue 536
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
41) chain B
residue 545
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
42) chain B
residue 573
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI18
43) chain B
residue 199
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:3759977, ECO:0000269|PubMed:6853480
source Swiss-Prot : SWS_FT_FI19
44) chain B
residue 233
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:15047055, ECO:0000269|PubMed:3759977
source Swiss-Prot : SWS_FT_FI20
45) chain B
residue 351
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:15047055, ECO:0000269|PubMed:3759977
source Swiss-Prot : SWS_FT_FI20
46) chain B
residue 318
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; in variant Redhill
source Swiss-Prot : SWS_FT_FI21
47) chain B
residue 494
type CARBOHYD
sequence D
description N-linked (GlcNAc...) asparagine; in variant Casebrook
source Swiss-Prot : SWS_FT_FI22
48) chain B
residue 525
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine => ECO:0000269|PubMed:15047055, ECO:0000269|PubMed:3759977, ECO:0000269|PubMed:6706980, ECO:0000269|PubMed:6853480
source Swiss-Prot : SWS_FT_FI23
49) chain B
residue 534
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; alternate => ECO:0000269|PubMed:3759977
source Swiss-Prot : SWS_FT_FI24
50) chain B
residue 5
type MOD_RES
sequence S
description Phosphoserine; by FAM20C => ECO:0000269|PubMed:26091039
source Swiss-Prot : SWS_FT_FI7
51) chain B
residue 58
type MOD_RES
sequence S
description Phosphoserine; by FAM20C => ECO:0000269|PubMed:26091039, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:24275569
source Swiss-Prot : SWS_FT_FI8
52) chain B
residue 65
type MOD_RES
sequence S
description Phosphoserine; by FAM20C => ECO:0000269|PubMed:26091039, ECO:0007744|PubMed:24275569
source Swiss-Prot : SWS_FT_FI9
53) chain B
residue 252
type BINDING
sequence E
description BINDING => ECO:0000250|UniProtKB:P02769
source Swiss-Prot : SWS_FT_FI2
54) chain B
residue 255
type BINDING
sequence D
description BINDING => ECO:0000250|UniProtKB:P02769
source Swiss-Prot : SWS_FT_FI2
55) chain B
residue 259
type BINDING
sequence D
description BINDING => ECO:0000250|UniProtKB:P02769
source Swiss-Prot : SWS_FT_FI2
56) chain B
residue 6
type BINDING
sequence E
description BINDING => ECO:0000250|UniProtKB:P02769
source Swiss-Prot : SWS_FT_FI2
57) chain B
residue 13
type BINDING
sequence D
description BINDING => ECO:0000250|UniProtKB:P02769
source Swiss-Prot : SWS_FT_FI2
58) chain B
residue 244
type BINDING
sequence E
description BINDING => ECO:0000250|UniProtKB:P02769
source Swiss-Prot : SWS_FT_FI2
59) chain B
residue 67
type BINDING
sequence H
description BINDING => ECO:0000269|PubMed:28567254, ECO:0007744|PDB:5IJF
source Swiss-Prot : SWS_FT_FI3
60) chain B
residue 247
type BINDING
sequence H
description BINDING => ECO:0000269|PubMed:28567254, ECO:0007744|PDB:5IJF
source Swiss-Prot : SWS_FT_FI3
61) chain B
residue 249
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:28567254, ECO:0007744|PDB:5IJF
source Swiss-Prot : SWS_FT_FI3
62) chain B
residue 240
type BINDING
sequence K
description BINDING => ECO:0000269|PubMed:656055
source Swiss-Prot : SWS_FT_FI4
63) chain B
residue 4
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
64) chain B
residue 20
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
65) chain B
residue 41
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
66) chain B
residue 64
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
67) chain B
residue 73
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
68) chain B
residue 93
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
69) chain B
residue 106
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
70) chain B
residue 136
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
71) chain B
residue 159
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
72) chain B
residue 174
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
73) chain B
residue 181
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
74) chain B
residue 190
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
75) chain B
residue 195
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
76) chain B
residue 205
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
77) chain B
residue 212
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
78) chain B
residue 240
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
79) chain B
residue 262
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
80) chain B
residue 274
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
81) chain B
residue 286
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
82) chain B
residue 359
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
83) chain B
residue 372
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
84) chain B
residue 389
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
85) chain B
residue 402
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
86) chain B
residue 414
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
87) chain B
residue 432
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
88) chain B
residue 436
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
89) chain B
residue 466
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
90) chain B
residue 475
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
91) chain B
residue 500
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
92) chain B
residue 519
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
93) chain B
residue 524
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
94) chain B
residue 538
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
95) chain B
residue 541
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
96) chain B
residue 557
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
97) chain B
residue 560
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
98) chain B
residue 564
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
99) chain B
residue 574
type SITE
sequence K
description Not glycated => ECO:0000269|PubMed:15047055
source Swiss-Prot : SWS_FT_FI5
100) chain B
residue 199
type SITE
sequence K
description Aspirin-acetylated lysine
source Swiss-Prot : SWS_FT_FI6
101) chain B
residue 83
type MOD_RES
sequence T
description Phosphothreonine; by FAM20C => ECO:0000269|PubMed:26091039
source Swiss-Prot : SWS_FT_FI10
102) chain B
residue 205
type MOD_RES
sequence K
description N6-succinyllysine => ECO:0000250|UniProtKB:P07724
source Swiss-Prot : SWS_FT_FI11
103) chain B
residue 436
type MOD_RES
sequence K
description N6-succinyllysine => ECO:0000250|UniProtKB:P07724
source Swiss-Prot : SWS_FT_FI11
104) chain B
residue 519
type MOD_RES
sequence K
description N6-succinyllysine => ECO:0000250|UniProtKB:P07724
source Swiss-Prot : SWS_FT_FI11
105) chain B
residue 564
type MOD_RES
sequence K
description N6-succinyllysine => ECO:0000250|UniProtKB:P07724
source Swiss-Prot : SWS_FT_FI11
106) chain B
residue 273
type MOD_RES
sequence S
description Phosphoserine => ECO:0000250|UniProtKB:P07724
source Swiss-Prot : SWS_FT_FI12

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