eF-site ID 3lp6-ABCD PDB Code 3lp6 Chain A, B, C, D click to enlarge Title Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution Classification LYASE Compound Phosphoribosylaminoimidazole carboxylase catalytic subunit Source null (PUR6_MYCTU) Sequence A:  ERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAH RTPEAMFSYARGAAARGLEVIIAGAGGAAHLPGMVAAATP LPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAG NAGLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAELQ RLAG B:  RPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHR TPEAMFSYARGAAARGLEVIIAGAGGAAHLPGMVAAATPL PVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGN AGLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAELQR LAGKLTR C:  AGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVS AHRTPEAMFSYARGAAARGLEVIIAGAGGAAHLPGMVAAA TPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGG AGNAGLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAE LQRLAGKLTR D:  MTPAGERPRVGVIMGSDSDWPVMADAAAALAEFDIPAEVR VVSAHRTPEAMFSYARGAAARGLEVIIAGAGGAAHLPGMV AAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVS IGGAGNAGLLAVRMLGAANPQLRARIVAFQDRLADVVAAK DAELQRLA Description Functional site 1) chain A residue 19 type sequence D description BINDING SITE FOR RESIDUE FMT A 175 source : AC1 2) chain A residue 71 type sequence G description BINDING SITE FOR RESIDUE FMT A 175 source : AC1 3) chain A residue 56 type sequence R description BINDING SITE FOR RESIDUE FMT A 176 source : AC2 4) chain A residue 82 type sequence A description BINDING SITE FOR RESIDUE FMT A 176 source : AC2 5) chain A residue 15 type sequence G description BINDING SITE FOR RESIDUE FMT A 177 source : AC3 6) chain A residue 43 type sequence S description BINDING SITE FOR RESIDUE FMT A 177 source : AC3 7) chain A residue 44 type sequence A description BINDING SITE FOR RESIDUE FMT A 177 source : AC3 8) chain A residue 45 type sequence H description BINDING SITE FOR RESIDUE FMT A 177 source : AC3 9) chain A residue 46 type sequence R description BINDING SITE FOR RESIDUE FMT A 177 source : AC3 10) chain A residue 47 type sequence T description BINDING SITE FOR RESIDUE FMT A 178 source : AC4 11) chain A residue 48 type sequence P description BINDING SITE FOR RESIDUE FMT A 178 source : AC4 12) chain A residue 49 type sequence E description BINDING SITE FOR RESIDUE FMT A 178 source : AC4 13) chain A residue 50 type sequence A description BINDING SITE FOR RESIDUE FMT A 178 source : AC4 14) chain B residue 15 type sequence G description BINDING SITE FOR RESIDUE GOL B 175 source : AC5 15) chain B residue 19 type sequence D description BINDING SITE FOR RESIDUE GOL B 175 source : AC5 16) chain B residue 70 type sequence A description BINDING SITE FOR RESIDUE GOL B 175 source : AC5 17) chain B residue 71 type sequence G description BINDING SITE FOR RESIDUE GOL B 175 source : AC5 18) chain B residue 95 type sequence L description BINDING SITE FOR RESIDUE GOL B 175 source : AC5 19) chain C residue 47 type sequence T description BINDING SITE FOR RESIDUE FMT B 176 source : AC6 20) chain C residue 48 type sequence P description BINDING SITE FOR RESIDUE FMT B 176 source : AC6 21) chain C residue 49 type sequence E description BINDING SITE FOR RESIDUE FMT B 176 source : AC6 22) chain C residue 50 type sequence A description BINDING SITE FOR RESIDUE FMT B 176 source : AC6 23) chain B residue 47 type sequence T description BINDING SITE FOR RESIDUE FMT B 177 source : AC7 24) chain B residue 48 type sequence P description BINDING SITE FOR RESIDUE FMT B 177 source : AC7 25) chain B residue 49 type sequence E description BINDING SITE FOR RESIDUE FMT B 177 source : AC7 26) chain B residue 50 type sequence A description BINDING SITE FOR RESIDUE FMT B 177 source : AC7 27) chain B residue 56 type sequence R description BINDING SITE FOR RESIDUE FMT B 178 source : AC8 28) chain B residue 82 type sequence A description BINDING SITE FOR RESIDUE FMT B 178 source : AC8 29) chain B residue 41 type sequence V description BINDING SITE FOR RESIDUE FMT B 179 source : AC9 30) chain B residue 15 type sequence G description BINDING SITE FOR RESIDUE FMT B 180 source : BC1 31) chain B residue 43 type sequence S description BINDING SITE FOR RESIDUE FMT B 180 source : BC1 32) chain B residue 44 type sequence A description BINDING SITE FOR RESIDUE FMT B 180 source : BC1 33) chain B residue 45 type sequence H description BINDING SITE FOR RESIDUE FMT B 180 source : BC1 34) chain B residue 46 type sequence R description BINDING SITE FOR RESIDUE FMT B 180 source : BC1 35) chain A residue 160 type sequence K description BINDING SITE FOR RESIDUE FMT B 181 source : BC2 36) chain B residue 16 type sequence S description BINDING SITE FOR RESIDUE FMT B 181 source : BC2 37) chain B residue 17 type sequence D description BINDING SITE FOR RESIDUE FMT B 181 source : BC2 38) chain B residue 46 type sequence R description BINDING SITE FOR RESIDUE FMT B 181 source : BC2 39) chain B residue 45 type sequence H description BINDING SITE FOR RESIDUE FMT B 182 source : BC3 40) chain B residue 46 type sequence R description BINDING SITE FOR RESIDUE FMT B 182 source : BC3 41) chain C residue 111 type sequence P description BINDING SITE FOR RESIDUE FMT B 182 source : BC3 42) chain A residue 150 type sequence Q description BINDING SITE FOR RESIDUE GOL C 175 source : BC4 43) chain A residue 151 type sequence D description BINDING SITE FOR RESIDUE GOL C 175 source : BC4 44) chain B residue 48 type sequence P description BINDING SITE FOR RESIDUE GOL C 175 source : BC4 45) chain C residue 56 type sequence R description BINDING SITE FOR RESIDUE GOL C 175 source : BC4 46) chain C residue 82 type sequence A description BINDING SITE FOR RESIDUE GOL C 175 source : BC4 47) chain C residue 83 type sequence A description BINDING SITE FOR RESIDUE GOL C 175 source : BC4 48) chain C residue 19 type sequence D description BINDING SITE FOR RESIDUE FMT C 176 source : BC5 49) chain C residue 70 type sequence A description BINDING SITE FOR RESIDUE FMT C 176 source : BC5 50) chain C residue 71 type sequence G description BINDING SITE FOR RESIDUE FMT C 176 source : BC5 51) chain C residue 32 type sequence E description BINDING SITE FOR RESIDUE FMT C 177 source : BC6 52) chain C residue 33 type sequence F description BINDING SITE FOR RESIDUE FMT C 177 source : BC6 53) chain C residue 145 type sequence R description BINDING SITE FOR RESIDUE FMT C 177 source : BC6 54) chain C residue 152 type sequence R description BINDING SITE FOR RESIDUE FMT C 177 source : BC6 55) chain B residue 160 type sequence K description BINDING SITE FOR RESIDUE FMT C 178 source : BC7 56) chain C residue 16 type sequence S description BINDING SITE FOR RESIDUE FMT C 178 source : BC7 57) chain C residue 17 type sequence D description BINDING SITE FOR RESIDUE FMT C 178 source : BC7 58) chain C residue 46 type sequence R description BINDING SITE FOR RESIDUE FMT C 178 source : BC7 59) chain C residue 15 type sequence G description BINDING SITE FOR RESIDUE FMT C 179 source : BC8 60) chain C residue 43 type sequence S description BINDING SITE FOR RESIDUE FMT C 179 source : BC8 61) chain C residue 44 type sequence A description BINDING SITE FOR RESIDUE FMT C 179 source : BC8 62) chain C residue 45 type sequence H description BINDING SITE FOR RESIDUE FMT C 179 source : BC8 63) chain D residue 47 type sequence T description BINDING SITE FOR RESIDUE FMT D 175 source : BC9 64) chain D residue 48 type sequence P description BINDING SITE FOR RESIDUE FMT D 175 source : BC9 65) chain D residue 49 type sequence E description BINDING SITE FOR RESIDUE FMT D 175 source : BC9 66) chain D residue 50 type sequence A description BINDING SITE FOR RESIDUE FMT D 175 source : BC9 67) chain D residue 15 type sequence G description BINDING SITE FOR RESIDUE FMT D 176 source : CC1 68) chain D residue 43 type sequence S description BINDING SITE FOR RESIDUE FMT D 176 source : CC1 69) chain D residue 44 type sequence A description BINDING SITE FOR RESIDUE FMT D 176 source : CC1 70) chain D residue 45 type sequence H description BINDING SITE FOR RESIDUE FMT D 176 source : CC1 71) chain A residue 41 type sequence V description BINDING SITE FOR RESIDUE FMT D 177 source : CC2 72) chain A residue 45 type sequence H description BINDING SITE FOR RESIDUE FMT D 178 source : CC3 73) chain D residue 82 type sequence A description BINDING SITE FOR RESIDUE FMT D 178 source : CC3 74) chain D residue 150 type sequence Q description BINDING SITE FOR RESIDUE FMT D 178 source : CC3 75) chain D residue 19 type sequence D description BINDING SITE FOR RESIDUE FMT D 179 source : CC4 76) chain D residue 71 type sequence G description BINDING SITE FOR RESIDUE FMT D 179 source : CC4 77) chain D residue 32 type sequence E description BINDING SITE FOR RESIDUE FMT D 180 source : CC5 78) chain D residue 145 type sequence R description BINDING SITE FOR RESIDUE FMT D 180 source : CC5 79) chain D residue 5 type sequence G description BINDING SITE FOR RESIDUE FMT D 181 source : CC6 80) chain B residue 16 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 81) chain B residue 19 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 82) chain B residue 46 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 83) chain C residue 16 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 84) chain C residue 19 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 85) chain C residue 46 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 86) chain D residue 16 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 87) chain D residue 19 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 88) chain D residue 46 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 89) chain A residue 16 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 90) chain A residue 19 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1 91) chain A residue 46 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_01929 source Swiss-Prot : SWS_FT_FI1

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