eF-site ID 3lmp-AC PDB Code 3lmp Chain A, C click to enlarge Title Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (NCOA1_HUMAN) Sequence A:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSP FVIYDMNSLMMGEDKIKFEQSKEVAIRIFQGCQFRSVEAV QEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASL MNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVK FNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNL LQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL QVIKKTETDMSLHPLLQEIYKDLY C:  RHKILHRLLQE Description Functional site 1) chain A residue 262 type sequence I description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 2) chain A residue 263 type sequence K description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 3) chain A residue 284 type sequence G description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 4) chain A residue 285 type sequence C description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 5) chain A residue 287 type sequence F description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 6) chain A residue 288 type sequence R description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 7) chain A residue 289 type sequence S description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 8) chain A residue 341 type sequence I description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 9) chain A residue 342 type sequence S description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 10) chain A residue 353 type sequence L description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 11) chain A residue 367 type sequence K description BINDING SITE FOR RESIDUE CEK A 23 source : AC1 12) chain A residue 473 type MOD_RES sequence Y description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 323 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 449 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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