eF-site/Summary 3ljz-ABCD

eF-site ID	3ljz-ABCD
PDB Code	3ljz
Chain	A, B, C, D

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Title	Crystal Structure of Human MMP-13 complexed with an Amino-2-indanol compound
Classification	HYDROLASE/HYDROLASE INHIBITOR
Compound	Collagenase 3
Source	Homo sapiens (Human) (MMP13_HUMAN)

Sequence	A:	ANVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFK VWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSG LLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHE FGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLY G
	B:	ANVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFK VWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSG LLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHE FGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQ SLYG
	C:	ANVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFK VWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSG LLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHE FGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQ SLYG
	D:	ANVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFK VWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSG LLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHE FGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQ SLYG

Description

Functional site


1)	chain	A
	residue	161
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE CA A 996
	source	: AC1

2)	chain	A
	residue	162
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA A 996
	source	: AC1

3)	chain	A
	residue	194
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE CA A 996
	source	: AC1

4)	chain	A
	residue	196
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA A 996
	source	: AC1

5)	chain	A
	residue	198
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA A 996
	source	: AC1

6)	chain	A
	residue	179
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA A 997
	source	: AC2

7)	chain	A
	residue	180
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA A 997
	source	: AC2

8)	chain	A
	residue	182
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE CA A 997
	source	: AC2

9)	chain	A
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE CA A 997
	source	: AC2

10)	chain	A
	residue	202
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA A 997
	source	: AC2

11)	chain	A
	residue	205
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE CA A 997
	source	: AC2

12)	chain	A
	residue	172
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN A 998
	source	: AC3

13)	chain	A
	residue	174
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE ZN A 998
	source	: AC3

14)	chain	A
	residue	187
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN A 998
	source	: AC3

15)	chain	A
	residue	200
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN A 998
	source	: AC3

16)	chain	A
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN A 999
	source	: AC4

17)	chain	A
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN A 999
	source	: AC4

18)	chain	A
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN A 999
	source	: AC4

19)	chain	A
	residue	120
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE SO4 A 1
	source	: AC5

20)	chain	A
	residue	139
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 A 1
	source	: AC5

21)	chain	A
	residue	155
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE SO4 A 1
	source	: AC5

22)	chain	A
	residue	115
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 A 5
	source	: AC6

23)	chain	A
	residue	116
	type
	sequence	M
	description	BINDING SITE FOR RESIDUE SO4 A 5
	source	: AC6

24)	chain	A
	residue	117
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE SO4 A 5
	source	: AC6

25)	chain	A
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

26)	chain	A
	residue	185
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

27)	chain	A
	residue	186
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

28)	chain	A
	residue	218
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

29)	chain	A
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

30)	chain	A
	residue	223
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

31)	chain	A
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

32)	chain	A
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

33)	chain	A
	residue	239
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

34)	chain	A
	residue	241
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

35)	chain	A
	residue	242
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

36)	chain	A
	residue	243
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

37)	chain	A
	residue	244
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

38)	chain	A
	residue	245
	type
	sequence	T
	description	BINDING SITE FOR RESIDUE LA3 A 801
	source	: AC7

39)	chain	B
	residue	161
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE CA B 996
	source	: AC8

40)	chain	B
	residue	162
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA B 996
	source	: AC8

41)	chain	B
	residue	194
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE CA B 996
	source	: AC8

42)	chain	B
	residue	196
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA B 996
	source	: AC8

43)	chain	B
	residue	198
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA B 996
	source	: AC8

44)	chain	B
	residue	179
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA B 997
	source	: AC9

45)	chain	B
	residue	180
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA B 997
	source	: AC9

46)	chain	B
	residue	182
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE CA B 997
	source	: AC9

47)	chain	B
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE CA B 997
	source	: AC9

48)	chain	B
	residue	202
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA B 997
	source	: AC9

49)	chain	B
	residue	205
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE CA B 997
	source	: AC9

50)	chain	B
	residue	172
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN B 998
	source	: BC1

51)	chain	B
	residue	174
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE ZN B 998
	source	: BC1

52)	chain	B
	residue	187
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN B 998
	source	: BC1

53)	chain	B
	residue	200
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN B 998
	source	: BC1

54)	chain	B
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN B 999
	source	: BC2

55)	chain	B
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN B 999
	source	: BC2

56)	chain	B
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN B 999
	source	: BC2

57)	chain	B
	residue	176
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE EPE B 3
	source	: BC3

58)	chain	B
	residue	190
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE EPE B 3
	source	: BC3

59)	chain	B
	residue	231
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE EPE B 3
	source	: BC3

60)	chain	B
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE EPE B 3
	source	: BC3

61)	chain	B
	residue	139
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 B 2
	source	: BC4

62)	chain	B
	residue	155
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE SO4 B 2
	source	: BC4

63)	chain	A
	residue	236
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE SO4 B 6
	source	: BC5

64)	chain	B
	residue	115
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 B 6
	source	: BC5

65)	chain	B
	residue	116
	type
	sequence	M
	description	BINDING SITE FOR RESIDUE SO4 B 6
	source	: BC5

66)	chain	B
	residue	117
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE SO4 B 6
	source	: BC5

67)	chain	B
	residue	183
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

68)	chain	B
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

69)	chain	B
	residue	185
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

70)	chain	B
	residue	186
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

71)	chain	B
	residue	218
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

72)	chain	B
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

73)	chain	B
	residue	223
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

74)	chain	B
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

75)	chain	B
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

76)	chain	B
	residue	238
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

77)	chain	B
	residue	239
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

78)	chain	B
	residue	241
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

79)	chain	B
	residue	242
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

80)	chain	B
	residue	243
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

81)	chain	B
	residue	244
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

82)	chain	B
	residue	245
	type
	sequence	T
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

83)	chain	B
	residue	247
	type
	sequence	T
	description	BINDING SITE FOR RESIDUE LA3 B 802
	source	: BC6

84)	chain	C
	residue	161
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE CA C 996
	source	: BC7

85)	chain	C
	residue	162
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA C 996
	source	: BC7

86)	chain	C
	residue	194
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE CA C 996
	source	: BC7

87)	chain	C
	residue	196
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA C 996
	source	: BC7

88)	chain	C
	residue	198
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA C 996
	source	: BC7

89)	chain	C
	residue	179
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA C 997
	source	: BC8

90)	chain	C
	residue	180
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA C 997
	source	: BC8

91)	chain	C
	residue	182
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE CA C 997
	source	: BC8

92)	chain	C
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE CA C 997
	source	: BC8

93)	chain	C
	residue	202
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA C 997
	source	: BC8

94)	chain	C
	residue	205
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE CA C 997
	source	: BC8

95)	chain	C
	residue	172
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN C 998
	source	: BC9

96)	chain	C
	residue	174
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE ZN C 998
	source	: BC9

97)	chain	C
	residue	187
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN C 998
	source	: BC9

98)	chain	C
	residue	200
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN C 998
	source	: BC9

99)	chain	C
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN C 999
	source	: CC1

100)	chain	C
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN C 999
	source	: CC1

101)	chain	C
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN C 999
	source	: CC1

102)	chain	C
	residue	176
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE EPE C 1
	source	: CC2

103)	chain	C
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE EPE C 1
	source	: CC2

104)	chain	C
	residue	187
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE EPE C 1
	source	: CC2

105)	chain	C
	residue	188
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE EPE C 1
	source	: CC2

106)	chain	C
	residue	189
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE EPE C 1
	source	: CC2

107)	chain	C
	residue	190
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE EPE C 1
	source	: CC2

108)	chain	C
	residue	120
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE SO4 C 3
	source	: CC3

109)	chain	C
	residue	139
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 C 3
	source	: CC3

110)	chain	C
	residue	155
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE SO4 C 3
	source	: CC3

111)	chain	C
	residue	115
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 C 7
	source	: CC4

112)	chain	C
	residue	116
	type
	sequence	M
	description	BINDING SITE FOR RESIDUE SO4 C 7
	source	: CC4

113)	chain	C
	residue	117
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE SO4 C 7
	source	: CC4

114)	chain	C
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

115)	chain	C
	residue	185
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

116)	chain	C
	residue	186
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

117)	chain	C
	residue	218
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

118)	chain	C
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

119)	chain	C
	residue	223
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

120)	chain	C
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

121)	chain	C
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

122)	chain	C
	residue	238
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

123)	chain	C
	residue	239
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

124)	chain	C
	residue	241
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

125)	chain	C
	residue	242
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

126)	chain	C
	residue	243
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

127)	chain	C
	residue	244
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

128)	chain	C
	residue	245
	type
	sequence	T
	description	BINDING SITE FOR RESIDUE LA3 C 803
	source	: CC5

129)	chain	D
	residue	162
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA D 996
	source	: CC6

130)	chain	D
	residue	194
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE CA D 996
	source	: CC6

131)	chain	D
	residue	196
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA D 996
	source	: CC6

132)	chain	D
	residue	198
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA D 996
	source	: CC6

133)	chain	D
	residue	179
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA D 997
	source	: CC7

134)	chain	D
	residue	180
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CA D 997
	source	: CC7

135)	chain	D
	residue	182
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE CA D 997
	source	: CC7

136)	chain	D
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE CA D 997
	source	: CC7

137)	chain	D
	residue	202
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CA D 997
	source	: CC7

138)	chain	D
	residue	205
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE CA D 997
	source	: CC7

139)	chain	D
	residue	172
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN D 998
	source	: CC8

140)	chain	D
	residue	174
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE ZN D 998
	source	: CC8

141)	chain	D
	residue	187
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN D 998
	source	: CC8

142)	chain	D
	residue	200
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN D 998
	source	: CC8

143)	chain	D
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN D 999
	source	: CC9

144)	chain	D
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN D 999
	source	: CC9

145)	chain	D
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN D 999
	source	: CC9

146)	chain	B
	residue	193
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE EPE D 2
	source	: DC1

147)	chain	B
	residue	194
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE EPE D 2
	source	: DC1

148)	chain	D
	residue	176
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE EPE D 2
	source	: DC1

149)	chain	D
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE EPE D 2
	source	: DC1

150)	chain	D
	residue	187
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE EPE D 2
	source	: DC1

151)	chain	D
	residue	189
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE EPE D 2
	source	: DC1

152)	chain	D
	residue	190
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE EPE D 2
	source	: DC1

153)	chain	D
	residue	133
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE EPE D 4
	source	: DC2

154)	chain	D
	residue	137
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE EPE D 4
	source	: DC2

155)	chain	D
	residue	140
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE EPE D 4
	source	: DC2

156)	chain	D
	residue	209
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE EPE D 4
	source	: DC2

157)	chain	D
	residue	217
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE EPE D 4
	source	: DC2

158)	chain	D
	residue	139
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 D 268
	source	: DC3

159)	chain	D
	residue	155
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE SO4 D 268
	source	: DC3

160)	chain	D
	residue	115
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE SO4 D 8
	source	: DC4

161)	chain	D
	residue	116
	type
	sequence	M
	description	BINDING SITE FOR RESIDUE SO4 D 8
	source	: DC4

162)	chain	D
	residue	117
	type
	sequence	N
	description	BINDING SITE FOR RESIDUE SO4 D 8
	source	: DC4

163)	chain	D
	residue	108
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE SO4 D 9
	source	: DC5

164)	chain	D
	residue	109
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE SO4 D 9
	source	: DC5

165)	chain	D
	residue	183
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

166)	chain	D
	residue	184
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

167)	chain	D
	residue	185
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

168)	chain	D
	residue	186
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

169)	chain	D
	residue	218
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

170)	chain	D
	residue	222
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

171)	chain	D
	residue	223
	type
	sequence	E
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

172)	chain	D
	residue	226
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

173)	chain	D
	residue	232
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

174)	chain	D
	residue	238
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

175)	chain	D
	residue	239
	type
	sequence	L
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

176)	chain	D
	residue	241
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

177)	chain	D
	residue	242
	type
	sequence	P
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

178)	chain	D
	residue	243
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

179)	chain	D
	residue	244
	type
	sequence	Y
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

180)	chain	D
	residue	245
	type
	sequence	T
	description	BINDING SITE FOR RESIDUE LA3 D 804
	source	: DC6

181)	chain	A
	residue	128
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

182)	chain	A
	residue	202
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

183)	chain	A
	residue	203
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

184)	chain	A
	residue	205
	type	BINDING
	sequence	E
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

185)	chain	B
	residue	128
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

186)	chain	B
	residue	162
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

187)	chain	B
	residue	179
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

188)	chain	B
	residue	180
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

189)	chain	B
	residue	182
	type	BINDING
	sequence	S
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

190)	chain	B
	residue	184
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

191)	chain	B
	residue	194
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

192)	chain	A
	residue	162
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

193)	chain	B
	residue	196
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

194)	chain	B
	residue	198
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

195)	chain	B
	residue	202
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

196)	chain	B
	residue	203
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

197)	chain	B
	residue	205
	type	BINDING
	sequence	E
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

198)	chain	C
	residue	128
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

199)	chain	C
	residue	162
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

200)	chain	C
	residue	179
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

201)	chain	C
	residue	180
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

202)	chain	C
	residue	182
	type	BINDING
	sequence	S
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

203)	chain	A
	residue	179
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

204)	chain	C
	residue	184
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

205)	chain	C
	residue	194
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

206)	chain	C
	residue	196
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

207)	chain	C
	residue	198
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

208)	chain	C
	residue	202
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

209)	chain	C
	residue	203
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

210)	chain	C
	residue	205
	type	BINDING
	sequence	E
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

211)	chain	D
	residue	128
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

212)	chain	D
	residue	162
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

213)	chain	D
	residue	179
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

214)	chain	A
	residue	180
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

215)	chain	D
	residue	180
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

216)	chain	D
	residue	182
	type	BINDING
	sequence	S
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

217)	chain	D
	residue	184
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

218)	chain	D
	residue	194
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

219)	chain	D
	residue	196
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

220)	chain	D
	residue	198
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

221)	chain	D
	residue	202
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

222)	chain	D
	residue	203
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

223)	chain	D
	residue	205
	type	BINDING
	sequence	E
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

224)	chain	A
	residue	182
	type	BINDING
	sequence	S
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

225)	chain	A
	residue	184
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

226)	chain	A
	residue	194
	type	BINDING
	sequence	N
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

227)	chain	A
	residue	196
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

228)	chain	A
	residue	198
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860, ECO:0000269\|PubMed:8969305
	source	Swiss-Prot : SWS_FT_FI2

229)	chain	A
	residue	223
	type	ACT_SITE
	sequence	E
	description	ACT_SITE => ECO:0000305\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI1

230)	chain	B
	residue	223
	type	ACT_SITE
	sequence	E
	description	ACT_SITE => ECO:0000305\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI1

231)	chain	C
	residue	223
	type	ACT_SITE
	sequence	E
	description	ACT_SITE => ECO:0000305\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI1

232)	chain	D
	residue	223
	type	ACT_SITE
	sequence	E
	description	ACT_SITE => ECO:0000305\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI1

233)	chain	A
	residue	219-228
	type	prosite
	sequence	VAAHEFGHSL
	description	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEFGHSL
	source	prosite : PS00142

234)	chain	A
	residue	172
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

235)	chain	B
	residue	174
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

236)	chain	B
	residue	187
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

237)	chain	B
	residue	200
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

238)	chain	B
	residue	222
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

239)	chain	B
	residue	226
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

240)	chain	B
	residue	232
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

241)	chain	B
	residue	240
	type	BINDING
	sequence	M
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

242)	chain	C
	residue	172
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

243)	chain	C
	residue	174
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

244)	chain	C
	residue	187
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

245)	chain	A
	residue	174
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

246)	chain	C
	residue	200
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

247)	chain	C
	residue	222
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

248)	chain	C
	residue	226
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

249)	chain	C
	residue	232
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

250)	chain	C
	residue	240
	type	BINDING
	sequence	M
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

251)	chain	D
	residue	172
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

252)	chain	D
	residue	174
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

253)	chain	D
	residue	187
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

254)	chain	D
	residue	200
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

255)	chain	D
	residue	222
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

256)	chain	A
	residue	187
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

257)	chain	D
	residue	226
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

258)	chain	D
	residue	232
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

259)	chain	D
	residue	240
	type	BINDING
	sequence	M
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

260)	chain	A
	residue	200
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

261)	chain	A
	residue	222
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

262)	chain	A
	residue	226
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

263)	chain	A
	residue	232
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

264)	chain	A
	residue	240
	type	BINDING
	sequence	M
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

265)	chain	B
	residue	172
	type	BINDING
	sequence	H
	description	BINDING => ECO:0000269\|PubMed:10926524, ECO:0000269\|PubMed:10986126, ECO:0000269\|PubMed:15734645, ECO:0000269\|PubMed:15780611, ECO:0000269\|PubMed:17196980, ECO:0000269\|PubMed:17623656, ECO:0000269\|PubMed:19422229, ECO:0000269\|PubMed:20005097, ECO:0000269\|PubMed:20726512, ECO:0000269\|PubMed:22689580, ECO:0000269\|PubMed:23810497, ECO:0000269\|PubMed:23913860
	source	Swiss-Prot : SWS_FT_FI3

266)	chain	A
	residue	117
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:8576151
	source	Swiss-Prot : SWS_FT_FI4

267)	chain	B
	residue	117
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:8576151
	source	Swiss-Prot : SWS_FT_FI4

268)	chain	C
	residue	117
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:8576151
	source	Swiss-Prot : SWS_FT_FI4

269)	chain	D
	residue	117
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:8576151
	source	Swiss-Prot : SWS_FT_FI4

270)	chain	A
	residue	152
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI5

271)	chain	B
	residue	152
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI5

272)	chain	C
	residue	152
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI5

273)	chain	D
	residue	152
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000255
	source	Swiss-Prot : SWS_FT_FI5