eF-site ID 3lhp-HILMST PDB Code 3lhp Chain H, I, L, M, S, T click to enlarge Title Crystal structure of HIV epitope-scaffold 4E10_D0_1ISEA_004_N 4E10 Fv complex Classification IMMUNE SYSTEM Compound Fv 4E10 heavy chain Source (3LHP) Sequence H:  VQLVQSGAEVKRPGSSVTVSCKASGGSFSTYALSWVRQAP GRGLEWMGGVIPLLTITNYAPRFQGRITITADRSTSTAYL ELNSLRPEDTAVYYCAREGTTGLGKPIGAFAHWGQGTLVT VSSL I:  VQLVQSGAEVKRPGSSVTVSCKASGGSFSTYALSWVRQAP GRGLEWMGGVIPLLTITNYAPRFQGRITITADRSTSTAYL ELNSLRPEDTAVYYCAREGTTGLGKPIGAFAHWGQGTLVT VS L:  EIVLTQSPGTQSLSPGERATLSCRASQSVGNNKLAWYQQR PGQAPRLLIYGASSRPSGVADRFSGSGSGTDFTLTISRLE PEDFAVYYCQQYGQSLSTFGQGTKVEVKLVP M:  EIVLTQSPGTQSLSPGERATLSCRASQSVGNNKLAWYQQR PGQAPRLLIYGASSRPSGVADRFSGSGSGTDFTLTISRLE PEDFAVYYCQQYGQSLSTFGQGTKVEVKLV S:  GSISDIRKDAEVRMDKAVEAFKNKLDKFKAAVRKVFPTEE RIKDWLKIVRGEAEQARVAVRNVGRDANDKAAALGKDKEI NWFDISQSLWDVQKLTDAAIKKIEAALADMEAWLTQ T:  DIRKDAEVRMDKAVEAFKNKLDKFKAAVRKVFPTEERIKD WLKIVRGEAEQARVAVRNVGRNDKAAALGKDKEINWFDIS QSLWDVQKLTDAAIKKIEAALADMEAWLTQ Description Functional site 1) chain M residue 38 type sequence Q description BINDING SITE FOR RESIDUE EDO M 113 source : AC1 2) chain M residue 48 type sequence L description BINDING SITE FOR RESIDUE EDO M 113 source : AC1 3) chain M residue 60 type sequence A description BINDING SITE FOR RESIDUE EDO M 113 source : AC1 4) chain M residue 63 type sequence F description BINDING SITE FOR RESIDUE EDO M 113 source : AC1

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