eF-site ID 3lcb-B PDB Code 3lcb Chain B click to enlarge Title The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli. Classification TRANSFERASE, HYDROLASE Compound Isocitrate dehydrogenase kinase/phosphatase Source Escherichia coli O157:H7 (strain EC4115 / EHEC) (IDH_ECOLI) Sequence B:  LELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ QAMKNRIHLYDHHVGLVVEQLRCITNEFLLRVKEHYTRLL PDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPER RFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKS RDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLV GKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVF GFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQ KHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPG FDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMA DTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVI RHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDI PPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGP LFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFS V Description Functional site 1) chain B residue 316 type sequence P description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 2) chain B residue 318 type sequence I description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 3) chain B residue 320 type sequence G description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 4) chain B residue 321 type sequence M description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 5) chain B residue 322 type sequence V description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 6) chain B residue 323 type sequence M description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 7) chain B residue 325 type sequence V description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 8) chain B residue 334 type sequence V description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 9) chain B residue 336 type sequence K description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 10) chain B residue 346 type sequence K description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 11) chain B residue 416 type sequence E description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 12) chain B residue 417 type sequence R description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 13) chain B residue 419 type sequence M description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 14) chain B residue 457 type sequence D description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 15) chain B residue 461 type sequence K description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 16) chain B residue 462 type sequence N description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 17) chain B residue 474 type sequence Y description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 18) chain B residue 475 type sequence D description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 19) chain B residue 477 type sequence D description BINDING SITE FOR RESIDUE ATP B 1761 source : AC4 20) chain B residue 104 type sequence N description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 21) chain B residue 105 type sequence S description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 22) chain B residue 113 type sequence H description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 23) chain B residue 116 type sequence L description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 24) chain B residue 291 type sequence K description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 25) chain B residue 294 type sequence K description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 26) chain B residue 295 type sequence T description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 27) chain B residue 298 type sequence Y description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 28) chain B residue 375 type sequence F description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 29) chain B residue 376 type sequence E description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 30) chain B residue 377 type sequence N description BINDING SITE FOR RESIDUE AMP B 1604 source : AC5 31) chain B residue 462 type sequence N description BINDING SITE FOR RESIDUE MG B 579 source : AC6 32) chain B residue 475 type sequence D description BINDING SITE FOR RESIDUE MG B 579 source : AC6

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