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|
eF-site ID
|
3l1p-ABMN |
|
PDB Code
|
3l1p |
|
Chain
|
A, B, M, N |
|
click to enlarge
|
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Title
|
POU protein:DNA complex |
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Classification
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TRANSCRIPTION/DNA |
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Compound
|
POU domain, class 5, transcription factor 1 |
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Source
|
null (3L1P) |
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Sequence
|
A: |
DMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGK
VFSQTTISRFEALQLSLKNMSKLRPLLEKWVEEADNNENL
QEISKSVQARKRKRTSIENRVRWSLETMFLKSPKPSLQQI
THIANQLGLEKDVVRVWFSNRRQKGKR
|
| B: |
KALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVF
SQTTISRFEALQLSLKNMSKLRPLLEKWVEEADNNENLQE
ISKSQARKRKRTSIENRVRWSLETMFLKSPKPSLQQITHI
ANQLGLEKDVVRVWFSNRRQKGKRS
|
| M: |
ATCCATTTGCCTTTCAAATGTGG
|
| N: |
TCCACATTTGAAAGGCAAATGGA
|
|
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Description
|
|
Functional site
|
|
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1)
|
chain |
A |
| residue |
20 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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2)
|
chain |
A |
| residue |
27 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
B |
| residue |
20 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
27 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
98 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0000250|UniProtKB:Q01860
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
B |
| residue |
98 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0000250|UniProtKB:Q01860
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
A |
| residue |
99 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:Q01860
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
8)
|
chain |
B |
| residue |
99 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:Q01860
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
9)
|
chain |
A |
| residue |
126-149 |
| type |
prosite |
| sequence |
IANQLGLEKDVVRVWFSNRRQKGK
|
| description |
HOMEOBOX_1 'Homeobox' domain signature. IAnqLgLEkdVVRVWFsNrrqkgK
|
| source |
prosite : PS00027
|
|
|
10)
|
chain |
A |
| residue |
19-31 |
| type |
prosite |
| sequence |
KRITLGYTQADVG
|
| description |
POU_1 POU-specific (POUs) domain signature 1. KRItLGYtQaDVG
|
| source |
prosite : PS00035
|
|
|
11)
|
chain |
A |
| residue |
43-56 |
| type |
prosite |
| sequence |
SQTTISRFEALQLS
|
| description |
POU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLqLS
|
| source |
prosite : PS00465
|
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