eF-site ID 3l1p-AB PDB Code 3l1p Chain A, B click to enlarge Title POU protein:DNA complex Classification TRANSCRIPTION/DNA Compound POU domain, class 5, transcription factor 1 Source Mus musculus (Mouse) (3L1P) Sequence A:  DMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGK VFSQTTISRFEALQLSLKNMSKLRPLLEKWVEEADNNENL QEISKSVQARKRKRTSIENRVRWSLETMFLKSPKPSLQQI THIANQLGLEKDVVRVWFSNRRQKGKR B:  KALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVF SQTTISRFEALQLSLKNMSKLRPLLEKWVEEADNNENLQE ISKSQARKRKRTSIENRVRWSLETMFLKSPKPSLQQITHI ANQLGLEKDVVRVWFSNRRQKGKRS Description Functional site 1) chain A residue 98 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:Q01860 source Swiss-Prot : SWS_FT_FI3 2) chain B residue 98 type MOD_RES sequence T description Phosphothreonine => ECO:0000250|UniProtKB:Q01860 source Swiss-Prot : SWS_FT_FI3 3) chain A residue 99 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q01860 source Swiss-Prot : SWS_FT_FI4 4) chain B residue 99 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q01860 source Swiss-Prot : SWS_FT_FI4 5) chain A residue 20 type BINDING sequence R description BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P source Swiss-Prot : SWS_FT_FI2 6) chain A residue 27 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P source Swiss-Prot : SWS_FT_FI2 7) chain B residue 20 type BINDING sequence R description BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P source Swiss-Prot : SWS_FT_FI2 8) chain B residue 27 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:23376973, ECO:0007744|PDB:3L1P source Swiss-Prot : SWS_FT_FI2 9) chain A residue 126-149 type prosite sequence IANQLGLEKDVVRVWFSNRRQKGK description HOMEOBOX_1 'Homeobox' domain signature. IAnqLgLEkdVVRVWFsNrrqkgK source prosite : PS00027 10) chain A residue 19-31 type prosite sequence KRITLGYTQADVG description POU_1 POU-specific (POUs) domain signature 1. KRItLGYtQaDVG source prosite : PS00035 11) chain A residue 43-56 type prosite sequence SQTTISRFEALQLS description POU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLqLS source prosite : PS00465

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