eF-site ID 3l0e-A
PDB Code 3l0e
Chain A

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Title X-ray crystal structure of a Potent Liver X Receptor Modulator
Classification TRANSCRIPTION
Compound Oxysterols receptor LXR-beta
Source Homo sapiens (Human) (NCOA2_HUMAN)
Sequence A:  QLTAAQELMIQQLVAAQLQSNKRSFSDQPKVTPWPLGADP
QSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGRE
DQIALLKASTIEIMLLETARRYNHETESITFLKDFTYSKD
DFHRAGLQVEFINPIFEFSRAMSSLGLDDAEYALLIAINI
FSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRF
PRMLMKLVSLRTLSSVHSEQVFALRLADAALPPLLSEIWD
VHE
Description


Functional site

1) chain A
residue 268
type
sequence F
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

2) chain A
residue 271
type
sequence F
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

3) chain A
residue 272
type
sequence T
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

4) chain A
residue 274
type
sequence L
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

5) chain A
residue 275
type
sequence A
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

6) chain A
residue 278
type
sequence S
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

7) chain A
residue 309
type
sequence I
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

8) chain A
residue 312
type
sequence M
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

9) chain A
residue 316
type
sequence T
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

10) chain A
residue 319
type
sequence R
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

11) chain A
residue 329
type
sequence F
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

12) chain A
residue 330
type
sequence L
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

13) chain A
residue 340
type
sequence F
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

14) chain A
residue 343
type
sequence A
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

15) chain A
residue 344
type
sequence G
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

16) chain A
residue 345
type
sequence L
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

17) chain A
residue 435
type
sequence H
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

18) chain A
residue 442
type
sequence L
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

19) chain A
residue 453
type
sequence L
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

20) chain A
residue 457
type
sequence W
description BINDING SITE FOR RESIDUE G58 A 1
source : AC1

21) chain A
residue 409
type CROSSLNK
sequence I
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000269|PubMed:20159957
source Swiss-Prot : SWS_FT_FI1

22) chain A
residue 447
type CROSSLNK
sequence A
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000269|PubMed:20159957
source Swiss-Prot : SWS_FT_FI1


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