eF-site ID 3kym-ABCDEFGHIJKLMNOP PDB Code 3kym Chain A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P click to enlarge Title Crystal structure of Li33 IgG2 di-Fab Classification IMMUNE SYSTEM Compound Light Chain Li33 IgG2 Source (3KYM) Sequence A:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRGE B:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVERK C:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRGE D:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVERK E:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRGE F:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVER G:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRGE H:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVER I:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRGE J:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVER K:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFPSDE QLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESV TEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSS PVTKSFNRG L:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVER M:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKS N:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVER O:  DIQMTQSPGTLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTEFTLTISSLQS EDFAVYYCQQYDKWPLTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRGE P:  EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYPMFWVRQA PGKGLEWVSWIGPSGGITKYADSVKGRFTISRDNSKNTLY LQMNSLRAEDTATYYCAREGHNDWYFDLWGRGTLVTVSSA STKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSNFGTQTY TCNVDHKPSNTKVDKTVER Description Functional site 1) chain A residue 192-198 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290 2) chain B residue 200-206 type prosite sequence YTCNVDH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290

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